Computed chest radiography for total body irradiation: image quality and clinical feasibility.

Autor:	Bouchez Q; Department of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, B-9000 Ghent, Belgium., Vandenbroucke D; R&D Imaging, Agfa N.V., Septestraat 27, B-2640 Mortsel, Belgium., Pittomvils G; Department of Radiotherapy-Oncology, Ghent University Hospital, Corneel Heymanslaan 10, B-9000 Ghent, Belgium., Boterberg T; Department of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, B-9000 Ghent, Belgium.; Department of Radiotherapy-Oncology, Ghent University Hospital, Corneel Heymanslaan 10, B-9000 Ghent, Belgium., van Eijkeren M; Department of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, B-9000 Ghent, Belgium.; Department of Radiotherapy-Oncology, Ghent University Hospital, Corneel Heymanslaan 10, B-9000 Ghent, Belgium., Leblans P; R&D Imaging, Agfa N.V., Septestraat 27, B-2640 Mortsel, Belgium., Vanderstraeten B; Department of Human Structure and Repair, Ghent University, Corneel Heymanslaan 10, B-9000 Ghent, Belgium.; Department of Radiotherapy-Oncology, Ghent University Hospital, Corneel Heymanslaan 10, B-9000 Ghent, Belgium.
Jazyk:	angličtina
Zdroj:	Biomedical physics & engineering express [Biomed Phys Eng Express] 2024 Jun 04; Vol. 10 (4). Date of Electronic Publication: 2024 Jun 04.
DOI:	10.1088/2057-1976/ad5018
Abstrakt:	Objective. In myeloablative total body irradiation (TBI), lung shielding blocks are used to reduce the dose to the lungs and hence decrease the risk of radiation pneumonitis. Some centers are still using mega-Volt (MV) imaging with dedicated silver halide-based films during simulation and treatment for lung delineation and position verification. However, the availability of these films has recently become an issue. This study examines the clinical performance of a computed radiography (CR) solution in comparison to radiographic films and potential improvement of image quality by filtering and post-processing. Approach. We compared BaFBrI-based CR plates to radiographic films. First, images of an aluminum block were analyzed to assess filter impact on scatter reduction. Secondly, a dedicated image quality phantom was used to assess signal linearity, signal-to-noise ratio (SNR), contrast and spatial resolution. Ultimately, a clinical performance study involving two impartial observers was conducted on an anthropomorphic chest phantom, employing visual grading analysis (VGA). Various filter materials and positions as well as post-processing were examined, and the workflow between CR and film was compared. Main results. CR images exhibited high SNR and linearity but demonstrated lower spatial and contrast resolution when compared to film. However, filtering improved contrast resolution and SNR, while positioning filters inside the cassette additionally enhanced sharpness. Image processing improved VGA scores, while additional filtering also resulted in higher spine visibility scores. CR shortened TBI simulation by over 10 minutes for one patient, alongside a dose reduction by order of 0.1 Gy. Significance. This study highlights potential advantages of shifting from conventional radiographic film to CR for TBI. Overall, CR with the incorporation of processing and filtering proves to be suitable for TBI chest imaging. When compared to radiographic film, CR offers advantages such as reduced simulation time and dose delivery, re-usability of image plates and digital workflow integration. (© 2024 The Author(s). Published by IOP Publishing Ltd.)
Databáze:	MEDLINE
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