Point-of-Care Bedside Brain Magnetic Resonance Imaging Is Safe in Extracorporeal Membrane Oxygenation Patients With Swan Ganz Catheters: A Phantom Experiment and Single Center Experience.

Autor: Chinedozi ID; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Boskamp E; Hyperfine Research, Guilford, Connecticut., Darby Z; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Kang JK; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Rando H; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Sair H; Department of Radiology, Johns Hopkins University, Baltimore, Maryland., Pitt J; Hyperfine Research, Guilford, Connecticut., Wilcox C; Critical Care Medicine, Mercy Hospital of Buffalo, Buffalo, New York., Kim BS; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Khanduja S; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Whitman G; Division of Cardiac Surgery, Johns Hopkins University, Baltimore, Maryland., Cho SM; Department of Neurology, Johns Hopkins University, Baltimore, Maryland. Electronic address: csungmi1@jhmi.edu.
Jazyk: angličtina
Zdroj: The Journal of surgical research [J Surg Res] 2024 Jul; Vol. 299, pp. 290-297. Date of Electronic Publication: 2024 May 23.
DOI: 10.1016/j.jss.2024.04.045
Abstrakt: Introduction: More than 1.2 million pulmonary artery catheters (PACs) are used in cardiac patients per annum within the United States. However, it is contraindicated in traditional 1.5 and 3T magnetic resonance imaging (MRI) scans. We aimed to test preclinical and clinical safety of using this imaging modality given the potential utility of needing it in the clinical setting.
Methods: We conducted two phantom experiments to ensure that the electromagnetic field power deposition associated with bare and jacketed PACs was safe and within the acceptable limit established by the Food and Drug Administration. The primary end points were the safety and feasibility of performing Point-of-Care (POC) MRI without imaging-related adverse events. We performed a preclinical computational electromagnetic simulation and evaluated these findings in nine patients with PACs on veno-arterial extracorporeal membrane oxygenation.
Results: The phantom experiments showed that the baseline point specific absorption rate through the head averaged 0.4 W/kg. In both the bare and jacketed catheters, the highest net specific absorption rates were at the neck entry point and tip but were negligible and unlikely to cause any heat-related tissue or catheter damage. In nine patients (median age 66, interquartile range 42-72 y) with veno-arterial extracorporeal membrane oxygenation due to cardiogenic shock and PACs placed for close hemodynamic monitoring, POC MRI was safe and feasible with good diagnostic imaging quality.
Conclusions: Adult ECMO patients with PACs can safely undergo point-of-care low-field (64 mT) brain MRI within a reasonable timeframe in an intensive care unit setting to assess for acute brain injury that might otherwise be missed with conventional head computed tomography.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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