Differences between psoriatic arthritis and psoriasis in multi-omics.

Autor: Gao S; Department of Rheumatology, Beijing Jishuitan Hospital, Guizhou Hospital, Guiyang, China.; Department of Rheumatology, Beijing Jishuitan Hospital, Capital Medical University, No.31, Xin Jie Kou East Street, Xicheng District, Beijing, 100035, China., Song H; Department of Rheumatology, Beijing Jishuitan Hospital, Capital Medical University, No.31, Xin Jie Kou East Street, Xicheng District, Beijing, 100035, China. jstyyfsmyk@163.com.
Jazyk: angličtina
Zdroj: Archives of dermatological research [Arch Dermatol Res] 2024 May 24; Vol. 316 (6), pp. 217. Date of Electronic Publication: 2024 May 24.
DOI: 10.1007/s00403-024-03018-9
Abstrakt: We aim to systemically review the genomics, transcriptomics, epigenetics, proteomics, metabonomics and microbiota of psoriatic arthritis and psoriasis, illustrating the differences of these two diseases, broadening our understanding of the pathogenesis of them and providing important clues for valuable biomarkers of earlier diagnosis and treatments. To our knowledge, this is the first study that combine all omics studies from genomics to microbiota and may serve as a reference for future studies to identify the key underlying pathways in psoriatic arthritis.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE