Factors affecting quality of life in hepatitis B patients in Herat, Afghanistan: A case-control study.

Autor: Shayan NA; Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Public Health and Infectious Disease, Faculty of Medicine, Herat University, Herat, Afghanistan., Rahimi A; Department of Curative Medicine, Faculty of Medicine, Jami University, Herat, Afghanistan.; Department of Pediatrics, Faculty of Medicine, Jami University, Herat, Afghanistan., Stranges S; Department of Public Health and Infectious Disease, Faculty of Medicine, Herat University, Herat, Afghanistan.; Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy., Thind A; Department of Public Health and Infectious Disease, Faculty of Medicine, Herat University, Herat, Afghanistan.; Department of Family Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Jazyk: angličtina
Zdroj: Journal of viral hepatitis [J Viral Hepat] 2024 Sep; Vol. 31 (9), pp. 511-523. Date of Electronic Publication: 2024 May 24.
DOI: 10.1111/jvh.13961
Abstrakt: Hepatitis B virus is a global health concern with a high death rate in Afghanistan. Limited data exist on the disease's impact on quality of life in low-resource settings. This case-control study aims to identify potential risk factors and assess the quality of life among hepatitis B patients in Herat, Afghanistan, with a focus on sex differences. Understanding these factors can inform prevention, care, and sex-specific interventions. A cross-sectional study conducted at Herat Regional Hospital examined hepatitis B patients above 18 years old, between October 2020 and February 2021. The control group consisted of age and sex-matched individuals without a history of hepatitis B. Data were collected through a structured questionnaire covering socio-demographic characteristics, signs and symptoms of hepatitis B, and the SF-36 questionnaire for measuring the quality of life of study participants. Statistical analysis was performed using multivariate General Linear Models, and logistic regression. We identified several potential risk factors for hepatitis B infection, including male sex, younger age groups, tobacco use, lower education levels, rural residence, family history, weak social networks, specific family structures and underlying chronic diseases (p < .05). The study found that hepatitis B cases had significantly lower mean scores across all SF-36 components, indicating an overall reduced quality of life (p < .05). These differences were more pronounced in males, although females had lower scores in most components. Role limitations due to physical and emotional health were particularly affected. These findings highlight the urgent need for targeted interventions, sex-specific strategies, improved healthcare access and comprehensive policies. These findings can inform prevention efforts to improve the overall quality of life of people with hepatitis B in Afghanistan.
(© 2024 The Author(s). Journal of Viral Hepatitis published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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