The Role of Nitrate Supply in Bioactive Compound Synthesis and Antioxidant Activity in the Cultivation of Porphyra linearis (Rhodophyta, Bangiales) for Future Cosmeceutical and Bioremediation Applications.

Autor:	Pereira DT; Experimental Center Grice Hutchinson, University Institute of Blue Biotechnology and Development (IBYDA), University of Malaga, Lomas de San Julián, 2, 29004 Málaga, Spain., Korbee N; Experimental Center Grice Hutchinson, University Institute of Blue Biotechnology and Development (IBYDA), University of Malaga, Lomas de San Julián, 2, 29004 Málaga, Spain., Vega J; Experimental Center Grice Hutchinson, University Institute of Blue Biotechnology and Development (IBYDA), University of Malaga, Lomas de San Julián, 2, 29004 Málaga, Spain., Figueroa FL; Experimental Center Grice Hutchinson, University Institute of Blue Biotechnology and Development (IBYDA), University of Malaga, Lomas de San Julián, 2, 29004 Málaga, Spain.
Jazyk:	angličtina
Zdroj:	Marine drugs [Mar Drugs] 2024 May 15; Vol. 22 (5). Date of Electronic Publication: 2024 May 15.
DOI:	10.3390/md22050222
Abstrakt:	Porphyra sensu lato has economic importance for food and pharmaceutical industries due to its significant physiological activities resulting from its bioactive compounds (BACs). This study aimed to determine the optimal nitrate dosage required in short-term cultivation to achieve substantial BAC production. A nitrate experiment using varied concentrations (0 to 6.5 mM) revealed optimal nitrate uptake at 0.5 mM in the first two days and at 3 and 5 mM in the last five days. Polyphenols and carbohydrates showed no differences between treatments, while soluble proteins peaked at 1.5 and 3 mM. Total mycosporine-like amino acids (MAAs) were highest in algae incubated at 5 and 6.5 mM, and the highest antioxidant activity was observed in the 5 mM, potentially related to the MAAs amount. Total carbon and sulfur did not differ between treatments, while nitrogen decreased at higher nitrate. This discovery highlights the nuanced role of nitrate in algal physiology, suggesting that biological and chemical responses to nitrate supplementation can optimize an organism's health and its commercially significant bioactive potential. Furthermore, given its ability to absorb high doses of nitrate, this alga can be cultivated in eutrophic zones or even in out-/indoor tanks, becoming an excellent option for integrated multi-trophic aquaculture (IMTA) and bioremediation. Competing Interests: The authors declare no conflicts of interest.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu