Prevalence of Kidney Dysfunction and Associated Risk Factors in a Southwestern City in Nigeria: A Cross-Sectional Study.

Autor:	Adejumo OA; Department of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria. E-mail: oluseyiadejumo2017@gmail.com., Junaid OA; Department of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria. E-mail: oluseyiadejumo2017@gmail.com., Egbi OG; Department of Internal Medicine, Niger Delta University, Bayelsa State, Nigeria., Edeki IR; Department of Internal Medicine, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria., Oyedepo DS; Department of Internal Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria., Fabusuyi O; Department of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria. E-mail: oluseyiadejumo2017@gmail.com., Akinyosoye GO; Department of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria. E-mail: oluseyiadejumo2017@gmail.com., Oloyede RO; Department of Internal Medicine, University of Medical Sciences, Ondo City, Ondo State, Nigeria. E-mail: oluseyiadejumo2017@gmail.com.
Jazyk:	angličtina
Zdroj:	West African journal of medicine [West Afr J Med] 2024 Mar 29; Vol. 41 (3), pp. 244-250.
Abstrakt:	Background: The burden of chronic kidney disease (CKD) is huge, especially in countries such as Nigeria where majority of patients succumb to the disease early due to inability to afford care. Early diagnosis through regular screening of at-risk population is pivotal to stemming the scourge of the disease. Aim: To determine the prevalence of kidney dysfunction and associated risk factors in a community screening program. Methods: This cross-sectional study assessed kidney dysfunction and associated risk factors among adults in Ondo City, Nigeria. Information about socio-demographic characteristics and some risk factors for kidney dysfunction was sought. Blood pressure, weight and height were measured. Blood samples were collected for random blood glucose check and serum creatinine while urine sample was collected for urinalysis. Kidney dysfunction was defined by estimated glomerular filtration rate (eGFR) below 60mls/min/1.73m2. Prevalence of kidney dysfunction and associated factors were determined. P value<0.05 was taken as significant. Results: There were 410 participants with a mean age of 58.96±13.78 years. Majority (75.1%) were female. One hundred and forty-seven (35.9%) participants had kidney dysfunction. Identified risk factors for kidney dysfunction were hypertension (72.7%), diabetes mellitus (18.0%), alcohol intake (13.2%), tobacco smoking (2%), analgesic use (82.7%), use of herbal preparations (81.7%), proteinuria (6.1%), overweight (27.8%), generalized obesity (28.5%), and central obesity (33.9%). Significant factors associated with kidney dysfunction were older age (p=<0.001), lower level of education (p=<0.001), and being hypertensive (p=0.019). On binary logistic regression, older age (AOR: 9.14; CI: 3.68-22.7; p=<0.001) was the only significant factor associated with kidney dysfunction. Conclusion: The prevalence of kidney dysfunction and that of associated risk factors were relatively high in the screened population. Regular assessment of kidney function should be done in those with higher risk of kidney dysfunction, especially older patients with hypertension. Competing Interests: The Authors declare that no competing interest exists (Copyright © 2024 by West African Journal of Medicine.)
Databáze:	MEDLINE
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