Multi-cancer early detection (MCED) tests: prioritizing equity from bench to bedside.

Autor: Miller SJ; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Department of Family Medicine and Community Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Sly JR; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Department of Family Medicine and Community Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Rolfo C; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Center for Thoracic Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Mack P; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Center for Thoracic Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Villanueva A; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Mount Sinai Liver Cancer Program, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Mazor M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Weber E; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Lin JJ; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Smith CB; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States., Taioli E; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Department of Thoracic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.; Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Jazyk: angličtina
Zdroj: Health affairs scholar [Health Aff Sch] 2024 May 23; Vol. 2 (5), pp. qxae039. Date of Electronic Publication: 2024 May 23 (Print Publication: 2024).
DOI: 10.1093/haschl/qxae039
Abstrakt: Multi-cancer early detection (MCED) tests are blood-based tests designed to screen for signals of multiple cancers. There is growing interest and investment in examining the potential benefits and applications of MCED tests. If MCED tests are shown to have clinical utility, it is important to ensure that all people-regardless of their demographic or socioeconomic background-equitably benefit from these tests. Unfortunately, with health care innovation, such considerations are often ignored until after inequities emerge. We urge for-profit companies, scientists, clinicians, payers, and government agencies to prioritize equity now-when MCEDs are still being developed and researched. In an effort to avoid creating and exacerbating cancer inequities, we propose 9 equity considerations for MCEDs.
Competing Interests: Conflicts of interest Please see ICMJE form(s) for author conflicts of interest. These have been provided as supplementary materials.
(© The Author(s) 2024. Published by Oxford University Press on behalf of Project HOPE - The People-To-People Health Foundation, Inc.)
Databáze: MEDLINE