Heavy metal poisoning caused by Chinese folk remedies in psoriasis patients: a retrospective analysis.

Autor: Xue C; Department of Occupational Medicine and Toxicology, Beijing Chao-Yang Hospital, Clinical Center for Interstitial Lung Diseases, Capital Medical University, Worker's Stadium No.8, Chao-Yang District, Beijing, 100020, China. yangtzesue123@sina.com., Du X; Department of Occupational Medicine and Toxicology, Beijing Chao-Yang Hospital, Clinical Center for Interstitial Lung Diseases, Capital Medical University, Worker's Stadium No.8, Chao-Yang District, Beijing, 100020, China., Zhu X; Department of Occupational Medicine and Toxicology, Beijing Chao-Yang Hospital, Clinical Center for Interstitial Lung Diseases, Capital Medical University, Worker's Stadium No.8, Chao-Yang District, Beijing, 100020, China., Wu N; Department of Occupational Medicine and Toxicology, Beijing Chao-Yang Hospital, Clinical Center for Interstitial Lung Diseases, Capital Medical University, Worker's Stadium No.8, Chao-Yang District, Beijing, 100020, China., Ye Q; Department of Occupational Medicine and Toxicology, Beijing Chao-Yang Hospital, Clinical Center for Interstitial Lung Diseases, Capital Medical University, Worker's Stadium No.8, Chao-Yang District, Beijing, 100020, China.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 May 23; Vol. 14 (1), pp. 11777. Date of Electronic Publication: 2024 May 23.
DOI: 10.1038/s41598-024-62653-4
Abstrakt: Psoriasis, characterized as a chronic relapsing disease with a protracted course, often drives patients to seek relief through Chinese folk remedies (CFR). Nonetheless, the complex compositions of these remedies frequently result in unintended adverse effects, notably various types of heavy metal poisoning. Our study involved an exhaustive collection and analysis of clinical data from psoriasis patients who developed heavy metal poisoning due to CFR usage, admitted to Beijing Chao-Yang Hospital from January 2011 to October 2023. Our analysis identified 44 cases of mercury poisoning, 17 of lead poisoning, 21 of arsenic poisoning, and 4 instances of mixed heavy metal poisoning. The folk remedies used ranged from fumigation and inhalation to skin application and oral administration. Distinct pathogenic characteristics were observed in each poisoning type. After treatment with metal chelating agents, all patients experienced a reduction in heavy metal levels in their bodies, accompanied by varying degrees of symptom alleviation. This study underscores the vital necessity of opting for formal, medically approved treatments for psoriasis, thereby avoiding the hazardous consequences of unregulated folk remedies that may lead to severe heavy metal poisoning.
(© 2024. The Author(s).)
Databáze: MEDLINE
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