The state of mental health among Ebola virus disease survivors through a cross-sectional study in Sierra Leone.

Autor:	Schindell BG; Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada., Fredborg B; Psychology, The University of Winnipeg, Winnipeg, Manitoba, Canada., Kowalec K; Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.; Medical Epidemiology & Biostatistics, Karolinska Institute, Stockholm, Sweden., Shaw S; Community Health Sciences, University of Manitoba Faculty of Health Sciences, Winnipeg, Manitoba, Canada., Kangbai JB; Public Health, Eastern Technical University of Sierra Leone, Kenema, Sierra Leone Jason.Kindrachuk@umanitoba.ca JKangbai@tulane.edu., Kindrachuk J; Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada Jason.Kindrachuk@umanitoba.ca JKangbai@tulane.edu.
Jazyk:	angličtina
Zdroj:	BMJ global health [BMJ Glob Health] 2024 May 23; Vol. 9 (5). Date of Electronic Publication: 2024 May 23.
DOI:	10.1136/bmjgh-2024-015098
Abstrakt:	Background: The West African Ebola virus disease (EVD) epidemic resulted in >28 000 disease cases and >11 000 fatalities. The unprecedented number of survivors from this epidemic has raised questions about the long-term mental health impacts of EVD survivorship and the capacity to meet these needs. Objectives: Assess the frequency and factors associated with mental health consequences of EVD survivorship in Sierra Leone. Methods: A cross-sectional study of 595 EVD survivors and 403 close contacts (n=998) from Sierra Leone assessed via in-person survey between November 2021 and March 2022. The assessment included validated mental health screening tools (Patient Health Questionnaire-9, PTSD Checklist-5, Alcohol Use Disorders Identification Test, Drug Abuse Screening Test-20) to indicate the presence/absence of disorder. The frequency of each disorder and factors associated with each disorder were assessed. Findings: EVD-associated post-traumatic stress disorder (PTSD) was reported by 45.7% (n=257) of EVD survivors. Moreover, 3.9% (n=22) and 12.0% (n=67) of EVD survivors reported major depression (MD) and substance use, respectively; all mental health outcomes were higher than baseline rates in the region (PTSD: 6%-16%, MD: 1.1%, substance use: 2.2%). PTSD among EVD survivors was associated with acute EVD duration of ≥21 days (adjusted OR, AOR 2.24, 95% CI 1.16 to 4.43), 35-44 years of age (AOR 3.31, 95% CI 1.33 to 8.24; AOR 2.99, 95% CI 1.09 to 8.24) and residential mobility (AOR 4.16, 95% CI 2.35 to 7.35). Conclusions: Concerningly, the levels of mental health disorders among EVD survivors in Sierra Leone remained elevated 6-8 years after recovery. Clinical Implications: Results can be used to inform policy efforts and target resources to address mental health in EVD survivors. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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