Advances in Microfluidic Paper-Based Analytical Devices (µPADs): Design, Fabrication, and Applications.

Autor: Chen JL; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China.; State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, P. R. China.; Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China., Njoku DI; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China., Tang C; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China., Gao Y; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China., Chen J; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China., Peng YK; Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China.; Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, P. R. China., Sun H; Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China.; Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, P. R. China., Mao G; School of Environmental Science and Engineering, Tianjin University, Tianjin, 300350, P. R. China., Pan M; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China., Tam NF; Department of Applied Science, School of Science and Technology, Hong Kong Metropolitan University, Good Shepherd Street, Ho Man Tin, Kowloon, Hong Kong SAR, P. R. China.; State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, P. R. China.; Shenzhen Research Institute of City University of Hong Kong, Shenzhen, 518057, P. R. China.; Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, P. R. China.
Jazyk: angličtina
Zdroj: Small methods [Small Methods] 2024 Nov; Vol. 8 (11), pp. e2400155. Date of Electronic Publication: 2024 May 23.
DOI: 10.1002/smtd.202400155
Abstrakt: Microfluidic Paper-based Analytical Devices (µPADs) have emerged as a new class of microfluidic systems, offering numerous advantages over traditional microfluidic chips. These advantages include simplicity, cost-effectiveness, stability, storability, disposability, and portability. As a result, various designs for different types of assays are developed and investigated. In recent years, µPADs are combined with conventional detection methods to enable rapid on-site detection, providing results comparable to expensive and sophisticated large-scale testing methods that require more time and skilled personnel. The application of µPAD techniques is extensive in environmental quality control/analysis, clinical diagnosis, and food safety testing, paving the way for on-site real-time diagnosis as a promising future development. This review focuses on the recent research advancements in the design, fabrication, material selection, and detection methods of µPADs. It provides a comprehensive understanding of their principles of operation, applications, and future development prospects.
(© 2024 Wiley‐VCH GmbH.)
Databáze: MEDLINE
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