| Autor: |
Tessele I; Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, Brazil., Dal Molin TR; Graduate Program of Pharmaceutical Sciences, Federal University of Santa Maria (UFSM), Santa Maria, Brazil., Dognini J; Instituto SENAI de Tecnologia Ambiental, Blumenau, Brazil., Noremberg S; Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, Brazil., de Carvalho LM; Department of Chemistry, Federal University of Santa Maria (UFSM), Santa Maria, Brazil.; Graduate Program of Pharmaceutical Sciences, Federal University of Santa Maria (UFSM), Santa Maria, Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2024 Jul; Vol. 41 (7), pp. 800-810. Date of Electronic Publication: 2024 May 23. |
| DOI: |
10.1080/19440049.2024.2354494 |
| Abstrakt: |
Dietary supplements are drastically growing as a category of consumer products all over the world. The abuse of supplements marketed for slimming purposes and physical fitness has been observed worldwide in recent years, which raises concerns in terms of public health. In this study, different types of dietary supplements marketed and delivered through the e -commerce were studied for the determination of thallium as a hazardous inorganic contaminant. The total content of thallium was determined by a sensitive voltammetric method after a microwave-assisted oxidative digestion of the sample. In addition, a comparative spectrometric method was applied for validation of the results in the samples. The maximum concentration found for thallium was found to be 2.89 mg kg -1 , which well agree with the comparative measurement. Considering the 32 studied formulations, it can be pointed out that ∼24% of the of dietary supplements presented Tl concentrations at concentrations higher than 1 mg kg -1 . The results permitted the assessment of the health risk related to thallium from contaminated samples, based on the calculation of the estimated daily intake (EDI) and the risk quotient (HQ). The highest daily intake of thallium was calculated as 82.0 µg day -1 in a protein-based supplement, which is equivalent to an EDI of 1.17 µg kg -1 day -1 . This work highlights the need to develop regulations on the limits of toxic elements such as thallium in widely consumed dietary supplements, as well as an in-depth look at the adverse effects caused by this element in the human body. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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