Aggregatibacter actinomycetemcomitans infection in children: two case reports and a review of the literature.

Autor: Karila-Cohen J; Department of General Pediatrics, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France. julie.karila-cohen@aphp.fr., Kerner S; Dental Faculty, Rothschild Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Universite Paris Cite, Paris, France., Blondiaux E; Department of Pediatric Radiology, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France., Vimont S; Department of Bacteriology, Saint Antoine Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France., Odièvre MH; Department of General Pediatrics, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France., Fournier B; Dental Faculty, Rothschild Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Universite Paris Cite, Paris, France., Grimprel E; Department of General Pediatrics, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France.; Groupe de Pathologie Infectieuse Pédiatrique (GPIP), 06200, Nice, France., Lorrot M; Department of General Pediatrics, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France.; Groupe de Pathologie Infectieuse Pédiatrique (GPIP), 06200, Nice, France., Romain AS; Department of General Pediatrics, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France.; Groupe de Pathologie Infectieuse Pédiatrique (GPIP), 06200, Nice, France.
Jazyk: angličtina
Zdroj: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2024 Jul; Vol. 43 (7), pp. 1487-1493. Date of Electronic Publication: 2024 May 23.
DOI: 10.1007/s10096-024-04853-4
Abstrakt: Aggregatibacter actinomycetemcomitans (Aa), a Gram-negative coccobacillus commonly associated with endocarditis, poses a rare diagnostic challenge in pediatric cases. The presentation of two pediatric cases-myositis and chest mass-highlights novel aspects, including unusual symptom presentations in children which can be mistaken for malignancy. The limited sensitivity of standard blood tests complicates diagnosis, leading to delayed diagnosis and treatment. Representative samples must be taken, especially if blood cultures are negative. Despite advances in detection methods, diagnosing Aa infection remains difficult due to its rarity in children and variable clinical presentation. In conclusion, a comprehensive understanding of Aa infection in children is essential for early and effective diagnostic and therapeutic management.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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