Area and individual level analyses of demographic and socio-economic disparities in COVID-19 vaccination uptake in Belgium.

Autor:	Hubin P; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Van den Borre L; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.; Interface Demography, Department of Sociology, Vrije Universiteit Brussel, Brussels, Belgium., Braeye T; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Cavillot L; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.; Research Institute of Health and Society, University of Louvain, Brussels, Belgium., Billuart M; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Stouten V; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Nasiadka L; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Vermeiren E; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Van Evercooren I; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., Devleesschauwer B; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.; Department of Translational Physiology, Infectiology and Public Health, Ghent University, Merelbeke, Belgium., Catteau L; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium., van Loenhout JAF; Department of Epidemiology and Public Health, Sciensano, Brussels, Belgium.
Jazyk:	angličtina
Zdroj:	Vaccine: X [Vaccine X] 2024 May 03; Vol. 18, pp. 100496. Date of Electronic Publication: 2024 May 03 (Print Publication: 2024).
DOI:	10.1016/j.jvacx.2024.100496
Abstrakt:	Vaccination has played a major role in overcoming the COVID-19 pandemic. However, vaccination status can be influenced by demographic and socio-economic factors at individual and area level. In the context of the LINK-VACC project, the Belgian vaccine register for the COVID-19 vaccination campaign was linked at individual level with other registers, notably the COVID-19 laboratory test results and demographic and socio-economic variables from the DEMOBEL database. The present article aims at investigating to which extent COVID-19 vaccination status is associated with area level and/or individual level demographic and socio-economic factors. From a sample of all individuals tested for SARS-CoV-2 (LINK-VACC sample) demographic and socio-economic indicators are derived and their impact on vaccination coverages at an aggregated geographical level (municipality) is quantified. The same indicators are calculated for the full Belgian population, allowing to assess the representativeness of the LINK-VACC sample with respect to the impact of demographic and socio-economic disparities on vaccination uptake. In a second step, hierarchical models are fitted to the individual level LINK-VACC data to disentangle the individual and municipality effects allowing to evaluate the added value of the availability of individual level data in this context. The most important effects observed at the individual level are reflected in the aggregated data at the municipality level. Multilevel analyses show that most of the demographic and socio-economic impacts on vaccination are captured at the individual level, although accounting for area level in individual level analyses improve the overall description. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2024 The Authors. Published by Elsevier Ltd.)
Databáze:	MEDLINE
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