The Caenorhabditis RNA-seq Browser: a web-based application for on-demand analysis of publicly available Caenorhabditis spp. bulk RNA-sequencing data.

Autor: Akimori D; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States.; Molecular Biology Interdepartmental Ph.D. Program, University of California, Los Angeles, Los Angeles, California, United States., Hillier LW; Department of Genome Sciences, University of Washington, Seattle, Washington, United States., Bryant AS; Department of Physiology and Biophysics, University of Washington, Seattle, Washington, United States.
Jazyk: angličtina
Zdroj: MicroPublication biology [MicroPubl Biol] 2024 May 07; Vol. 2024. Date of Electronic Publication: 2024 May 07 (Print Publication: 2024).
DOI: 10.17912/micropub.biology.001208
Abstrakt: The Caenorhabditis RNA-seq Browser is an open-source Shiny web app that enables on-demand visualization and quantification of bulk RNA-sequencing data for five Caenorhabditis species: C. elegans , C. briggsae , C. brenneri , C. japonica , and C. remanei . The app is designed to allow researchers without previous coding experience to interactively explore publicly available Caenorhabditis RNA-sequencing data. Key app features include the ability to plot gene expression across life stages for user-specified gene sets, and modules for performing differential gene expression analyses. The Caenorhabditis RNA-seq Browser can be accessed online via shinyapps.io or can be installed locally in R from a GitHub repository.
Competing Interests: The authors declare that there are no conflicts of interest present.
(Copyright: © 2024 by the authors.)
Databáze: MEDLINE