Autor: |
Lucia F; Département de Radiothérapie-Oncologie, Hôpital Universitaire de Brest, France.; LaTIM, INSERM, UMR 1101, Université de Brest, France.; Service de Médecine nucléaire et d'Imagerie oncologique, CHU Liège, Belgique., Withofs N; Service de Médecine nucléaire et d'Imagerie oncologique, CHU Liège, Belgique.; GIGA-CRC in vivo Imaging, ULiège, Belgique., Lovinfosse P; Service de Médecine nucléaire et d'Imagerie oncologique, CHU Liège, Belgique.; GIGA-CRC in vivo Imaging, ULiège, Belgique., Hustinx R; Service de Médecine nucléaire et d'Imagerie oncologique, CHU Liège, Belgique.; GIGA-CRC in vivo Imaging, ULiège, Belgique. |
Abstrakt: |
Functional imaging, including positron emission tomography combined with computed tomography (PET/CT), allows the evaluation of numerous biological properties that could be considered at all steps of the therapeutic management of patients treated with radiotherapy. Indeed, it enables better initial staging of the disease, and some parameters may also be used as predictive biomarkers for treatment response, allowing better selection of patients eligible for radiotherapy. It may also improve the definition of target volumes with the aim of dose escalations by dose-painting. Finally, it could be useful during the follow-up to assess response to treatment. In this review, we report how functional imaging is integrated at the present time during the radiotherapy procedure, and what are its potential future contributions. |