We are what we eat: macrophages and efferocytosis.
Autor: | Cunningham KT; School of Infection and Immunity, University of Glasgow, Glasgow, UK. Electronic address: Kyle.Cunningham@glasgow.ac.uk., Maizels RM; School of Infection and Immunity, University of Glasgow, Glasgow, UK. |
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Jazyk: | angličtina |
Zdroj: | Trends in parasitology [Trends Parasitol] 2024 Jun; Vol. 40 (6), pp. 446-448. Date of Electronic Publication: 2024 May 20. |
DOI: | 10.1016/j.pt.2024.05.004 |
Abstrakt: | Liebold et al. recently revealed how the identity of dying cells drives distinct changes to the macrophages which engulf and clear them, a process known as efferocytosis. During infection with the helminth Schistosoma mansoni, liver macrophages recapitulate these phenotypes, mediated by Axl/MerTK receptors and regulating egg burdens. Competing Interests: Declaration of interests The authors declare no competing interests. (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
Databáze: | MEDLINE |
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