We are what we eat: macrophages and efferocytosis.

Autor: Cunningham KT; School of Infection and Immunity, University of Glasgow, Glasgow, UK. Electronic address: Kyle.Cunningham@glasgow.ac.uk., Maizels RM; School of Infection and Immunity, University of Glasgow, Glasgow, UK.
Jazyk: angličtina
Zdroj: Trends in parasitology [Trends Parasitol] 2024 Jun; Vol. 40 (6), pp. 446-448. Date of Electronic Publication: 2024 May 20.
DOI: 10.1016/j.pt.2024.05.004
Abstrakt: Liebold et al. recently revealed how the identity of dying cells drives distinct changes to the macrophages which engulf and clear them, a process known as efferocytosis. During infection with the helminth Schistosoma mansoni, liver macrophages recapitulate these phenotypes, mediated by Axl/MerTK receptors and regulating egg burdens.
Competing Interests: Declaration of interests The authors declare no competing interests.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE