Skull base surgery for malignant tumors: The 2nd international collaborative study (1995-2015).

Autor: Shah JP; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Levyn H; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Valero C; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Adilbay D; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Eagan A; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Zheng J; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Gonen M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Cohen M; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Patel S; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Ganly I; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Pai P; Head and Neck Surgical Oncology, Tata Memorial Hospital, Mumbai, India., Castelnuovo P; Department of Otorhinolaryngology, University of Insubria, Varese, Italy., Gao FJ; Department of Head and Neck Surgery, Beijing Tongren Hospital, Beijing, China., Piazza C; Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia, Spedali Civili BS Piazzale Spedali Civili, Brescia, Italy., Nicolai P; Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia, Spedali Civili BS Piazzale Spedali Civili, Brescia, Italy., Panizza B; Department of Head & Neck Oncology, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia., Bowman J; Department of Head & Neck Oncology, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia., Barnett C; Department of Head & Neck Oncology, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia., Kowalski LP; Head and Neck Reference Center, AC Camargo, Sao Paulo, Brazil.; Head and Neck Service, ICESP, São Paulo, Brazil., Toledo R; Head and Neck Reference Center, AC Camargo, Sao Paulo, Brazil., Fliss DM; University of Nicosia Medical School, Cyprus., DeAlmeida J; Department of Otolaryngology - Head & Neck Surgery, University Health Network, Toronto, Ontario, Canada., Witterick I; Department of Otolaryngology - Head & Neck Surgery, University Health Network, Toronto, Ontario, Canada., Herman P; ENT Department - Skull Base Center, Hispital Lariboisiere APHP, Paris, France., Fontanella W; Unit of Otorhinolaryngology - Maxillofacial, and Thyroid Surgery, University of Milan, Milan, Italy., Aniceto GS; Oral and Maxillofacial Department, 12 de Octubre University Hospital, Madrid, Spain., Hosal S; Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Atılım University, Medicana International Ankara, Ankara, Turkey., Ozer S; Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Atılım University, Medicana International Ankara, Ankara, Turkey., Iyer S; Department of Head and Neck Surgery and Oncology, Amrita Institute of Medical Sciences, Kochi, India., Harvey R; Sydney Ear Nose Throat Clinic, Darlinghurst, New South Wales, Australia., Leemans CR; Otolaryngology-Head and Neck Surgery, Amsterdam University Medical Center, VU University, Amsterdam, The Netherlands., Hendrickx JJ; Otolaryngology-Head and Neck Surgery, Amsterdam University Medical Center, VU University, Amsterdam, The Netherlands., Figari M; Head and Neck Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Boccalatte L; Head and Neck Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina., Nibu KI; Department of Otolaryngology - Head & Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan., Clarke P; ENT Department, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, United Kingdom., Rennie C; ENT Department, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, United Kingdom., Ming ZY; Head and Neck Surgery, Beijing Cancer Center, Beijing, China., Cernea C; Head and Neck Service, ICESP, São Paulo, Brazil., Goncalves S; Head and Neck Service, ICESP, São Paulo, Brazil., Schlosser R; Department of Otolaryngology - Head & Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA., Dias F; Department of Head and Neck Surgery, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Sargi Z; Department of Otolaryngology, University of Miami, Miami, Florida, USA., Ahmed S; Department of Otolaryngology - Head and Neck Surgery, University of Birmingham, University Hospitals Birmingham, Birmingham, United Kingdom., Golusinski W; Department of Head and Neck Surgery, The Greater Poland Cancer Centre, Poznan, Poland., Kim SH; Department of ENT, Yonsei University Health System, Seoul, South Korea., Su SY; Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas, USA., Raza SM; Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas, USA., DeMonte F; Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas, USA., Hanna E; Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas, USA.
Jazyk: angličtina
Zdroj: Head & neck [Head Neck] 2024 Nov; Vol. 46 (11), pp. 2762-2775. Date of Electronic Publication: 2024 May 21.
DOI: 10.1002/hed.27746
Abstrakt: Background: The current study presents the effort of a global collaborative group to review the management and outcomes of malignant tumors of the skull base worldwide.
Patients and Methods: A total of 28 institutions contributed data on 3061 patients. Analysis evaluated clinical variables, survival outcomes, and multivariable factors associated with outcomes.
Results: The median age was 56 years (IQR 44-67). The open surgical approach was used in 55% (n = 1680) of cases, endoscopic resection was performed in 36% (n = 1087), and the combined approach in 9.6% (n = 294). With a median follow-up of 7.1 years, the 5-year OS DSS and RFS were 65%, 71.7% and 53%, respectively. On multivariable analysis, older age, comorbidities, histology, dural/intracranial involvement, positive margins, advanced stage, and primary site were independent prognostic factors for OS, DSS, and RFS. Adjuvant RT was a protective prognostic factor.
Conclusion: The progress across various disciplines may have contributed to improved OS and DSS in this study compared to previous reports.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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