Leukemic infiltration of the ciliary body in a child with T-cell acute lymphoblastic leukemia.

Autor: Villagomez-Valdez LG; Tecnologico de Monterrey, School of Medicine and Health Sciences., Colorado-Zavala MF; Tecnologico de Monterrey, School of Medicine and Health Sciences., Ruiz-Lozano RE; Tecnologico de Monterrey, School of Medicine and Health Sciences., Gonzalez E; Boston Children's Hospital, Boston, Massachusetts., Gomez-Valdez L; Private Practice, Guadalajara, Jalisco, Mexico., Gonzalez-Ramella O; Onkokid, Puerta de Hierro, Zapopan, Mexico., Ancona-Lezama D; Eye Cancer Institute, Monterrey, Mexico. Electronic address: davidancona@eyecancerinstitute.com.
Jazyk: angličtina
Zdroj: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus [J AAPOS] 2024 Aug; Vol. 28 (4), pp. 103937. Date of Electronic Publication: 2024 May 19.
DOI: 10.1016/j.jaapos.2024.103937
Abstrakt: A 14-year-old boy presented after 2 months of vision loss, redness, and pain in the right eye, initially treated as anterior uveitis with topical corticosteroids. He had a 1-year history of T-cell acute lymphoblastic leukemia, which had been in remission for 6 months. On examination, visual acuity in the right eye was light perception, with 4+ anterior chamber cells, pupillary membrane, and an intumescent cataract. Ultrasound biomicroscopy (UBM) revealed a ciliary body mass and capsular bag rupture. After consultation with his oncologist, he received 10 radiotherapy sessions. At 1 month, UBM showed resolution of the mass. After 1 year of remission, the patient underwent pars plana vitrectomy, pupillary membranectomy, and placement of a scleral-fixated intraocular lens. Thirty months after surgery, visual acuity was 20/25. Leukemic infiltration of the ciliary body is a rare manifestation of the disease that is often misdiagnosed as uveitis.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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