Female obesity: clinical and psychological assessment toward the best treatment.
| Autor: | Guglielmi V; Unit of Internal Medicine and Obesity Center, Department of Systems Medicine, Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy., Dalle Grave R; Department of Eating and Weight Disorders, Villa Garda Hospital, Garda, VR, Italy., Leonetti F; Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy., Solini A; Department of Surgical, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 May 03; Vol. 15, pp. 1349794. Date of Electronic Publication: 2024 May 03 (Print Publication: 2024). |
| DOI: | 10.3389/fendo.2024.1349794 |
| Abstrakt: | Obesity is a heterogeneous condition which results from complex interactions among sex/gender, sociocultural, environmental, and biological factors. Obesity is more prevalent in women in most developed countries, and several clinical and psychological obesity complications show sex-specific patterns. Females differ regarding fat distribution, with males tending to store more visceral fat, which is highly correlated to increased cardiovascular risk. Although women are more likely to be diagnosed with obesity and appear more motivated to lose weight, as confirmed by their greater representation in clinical trials, males show better outcomes in terms of body weight and intra-abdominal fat loss and improvements in the metabolic risk profile. However, only a few relatively recent studies have investigated gender differences in obesity, and sex/gender is rarely considered in the assessment and management of the disease. This review summarizes the evidence of gender differences in obesity prevalence, contributing factors, clinical complications, and psychological challenges. In addition, we explored gender differences in response to obesity treatments in the specific context of new anti-obesity drugs. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision. (Copyright © 2024 Guglielmi, Dalle Grave, Leonetti and Solini.) |
| Databáze: | MEDLINE |
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