Predictive value of TCCD and regional cerebral oxygen saturation for detecting early postoperative brain injury.
Autor: | Liu Y; Graduate School of Dalian Medical University, Liaoning, 116044, China., Zhao L; Department of Anesthesiology, Nanjing Medical University Affiliated, Changzhou No. 2 People's Hospital, Changzhou, 213003, China., Wang X; Graduate School of Dalian Medical University, Liaoning, 116044, China., Wu Z; Department of Anesthesiology, Nanjing Medical University Affiliated, Changzhou No. 2 People's Hospital, Changzhou, 213003, China. wuzhouquan2005@126.com. |
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Jazyk: | angličtina |
Zdroj: | Journal of clinical monitoring and computing [J Clin Monit Comput] 2024 Oct; Vol. 38 (5), pp. 1079-1087. Date of Electronic Publication: 2024 May 17. |
DOI: | 10.1007/s10877-024-01165-y |
Abstrakt: | Objective: This study aims to analyze the risk factors for early postoperative brain injury in patients undergoing cardiovascular surgery and explore the predictive value of transcranial color Doppler (TCCD) and regional cerebral oxygen saturation (rSO Methods: A total of 55 patients undergoing cardiovascular surgery with cardiopulmonary bypass in Changzhou No.2 The People's Hospital of Nanjing Medical University were included in this study. Neuron-specific enolase (NSE) concentration was measured 24 h after operation. Patients were divided into brain injury (NSE ≥ 16.3 ng/mL) and normal (0 < NSE < 16.3 ng/mL) groups according to the measured NSE concentration. The clinical outcomes between the two groups were compared, including decreased rSO Results: A total of 50 patients were included in this study, with 20 patients in the brain injury group and 30 patients in the normal group. Cardiopulmonary bypass time (min) (107 ± 29 vs. 90 ± 28, P = 0.047) and aortic occlusion time (min) (111 (IQR 81-127) vs. 87 (IQR 72-116), P = 0.010) were significantly longer in the brain injury group than in the normal group. Patients in the brain injury group had greater decreased rSO Conclusion: The decreased rSO (© 2024. The Author(s).) |
Databáze: | MEDLINE |
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