| Autor: |
Cuong DV; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.; National Institute of Medicinal Materials, Ministry of Health, Hanoi, Vietnam.; University of Medicine and Pharmacy (VNU-UMP), Vietnam National University Hanoi, Hanoi, Vietnam., Hanh TTH; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam., Huong PTM; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam., Huong NT; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam., Quang TH; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam., Cuong NX; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam. |
| Abstrakt: |
Using various chromatographic separations, six glycoside derivatives ( 1-6 ), including one new ent -labdane glucoside named cayratioside ( 1 ), were isolated from the methanol extract of Cayratia geniculata stems and leaves. Their structures were elucidated by detailed analysis of the 1D, 2D NMR, and HRESIQTOF mass spectra. The inhibitory effect of 1-6 on LPS-induced NO production in RAW264.7 cells was also evaluated. Among isolated compounds, 1 exhibited moderate activity with an IC 50 value of 59.65 ± 1.85 µM. |
