Synthetic approach to iodosulfuron-methyl and metsulfuron-methyl metabolites and their application for water analysis.
| Autor: | Rakowiecki M; Synthex Technologies Sp. z o.o. Gagarina 7/134B 87-100 Toruń Poland budny@synthex.com.pl., Studzińska S; Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland., Ścianowski J; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland., Bosiak MJ; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland.; Noctiluca S.A. Gagarina 7/41B 87-100 Toruń Poland., Wolan A; Synthex Technologies Sp. z o.o. Gagarina 7/134B 87-100 Toruń Poland budny@synthex.com.pl.; Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University Gagarina 7 87-100 Toruń Poland., Budny M; Synthex Technologies Sp. z o.o. Gagarina 7/134B 87-100 Toruń Poland budny@synthex.com.pl. |
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| Jazyk: | angličtina |
| Zdroj: | RSC advances [RSC Adv] 2024 May 15; Vol. 14 (23), pp. 15848-15855. Date of Electronic Publication: 2024 May 15 (Print Publication: 2024). |
| DOI: | 10.1039/d4ra01725k |
| Abstrakt: | A synthetic approach to ten metabolites of iodosulfuron-methyl sodium and metsulfuron-methyl was performed and reported in this study. The compounds of interest were prepared by controlled hydrolytic degradation of active substances or by de novo synthesis from commercially available triazine precursor 10. Obtained compounds were characterized by IR, NMR, and elemental analysis techniques. Metabolites and active substances were utilized during the development of a separation and quantification method using reversed-phase high-performance liquid chromatography coupled with tandem mass spectrometry. The validated method was applied for the analysis of all studied compounds in the extracts from water samples collected from the Vistula river (Toruń, Poland). Competing Interests: There are no conflicts to declare. (This journal is © The Royal Society of Chemistry.) |
| Databáze: | MEDLINE |
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