Autor: |
Bos RJ, Serruys PW, Brower RW, ten Katen HJ, Vanhaleweyk G, Hugenholtz PG |
Jazyk: |
angličtina |
Zdroj: |
European heart journal [Eur Heart J] 1985 Apr; Vol. 6 (4), pp. 349-57. |
DOI: |
10.1093/oxfordjournals.eurheartj.a061862 |
Abstrakt: |
15 patients, 1 to 3 year after coronary bypass surgery, underwent symptom limited supine bicycle exercise tests without nifedipine and after acute and chronic (3 months) administration of the drug. Haemodynamic variables were monitored as was epicardial marker motion, using biplane cineradiography during exercise, the markers having been implanted at the time of surgery. We found significant (P less than 0.001) reductions in end-diastolic and end-systolic regional dimensions at maximal exercise after oral nifedipine, associated with a significant reduction in exertional angina, which persisted during long-term treatment. No adverse effects of the drug were observed. |
Databáze: |
MEDLINE |
Externí odkaz: |
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