Clinically significant incidental noncardiac findings on preprocedural computed tomography in patients with aortic stenosis undergoing aortic-valve replacement.

Autor: Yamamoto K; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Takeji Y; Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan., Taniguchi T; Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Kobe, Japan., Morimoto T; Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan., Tabata H; Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Ishizu K; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Morofuji T; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Hayashi M; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Isotani A; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Shirai S; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Ohno N; Department of Cardiovascular Surgery, Kokura Memorial Hospital, Kitakyushu, Japan., Kakumoto S; Department of Anesthesiology, Kokura Memorial Hospital, Kitakyushu, Japan., Ando K; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan., Minatoya K; Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Kimura T; Department of Cardiology, Hirakata Kohsai Hospital, Hirakata, Japan. Electronic address: taketaka@kuhp.kyoto-u.ac.jp.
Jazyk: angličtina
Zdroj: Journal of cardiology [J Cardiol] 2024 Nov; Vol. 84 (5), pp. 326-332. Date of Electronic Publication: 2024 May 15.
DOI: 10.1016/j.jjcc.2024.05.006
Abstrakt: Background: There is a scarcity of data on the prevalence of abnormal findings on preprocedural computed tomography (CT) before aortic valve replacement (AVR) in patients with aortic stenosis (AS).
Methods: Among consecutive 593 patients with severe AS who were planned to undergo AVR, we evaluated the prevalence of clinically significant incidental noncardiac findings on preprocedural CT. Clinically significant incidental noncardiac findings were defined as newly detected abnormalities that required therapy, consultation for expert, further investigation, or clinical follow-up.
Results: The mean age was 82.0 years and 39.5 % of the patients were men. Of those, 78.4 % of the patients were treated with transcatheter aortic valve implantation (TAVI) and 21.6 % of the patients were treated with surgical AVR (SAVR). There were 271 clinically significant incidental noncardiac findings in 227 patients (38.3 %) including 2.5 % of malignancy. The prevalence of clinically significant incidental noncardiac findings were higher in the TAVI group than in the SAVR group (40.2 % versus 31.3 %). The prevalence of clinically significant incidental noncardiac findings were lower in patients under 60 years of age (10.0 %) than in patients over 60 years of age (60-69 years: 40.0 %, 70-79 years: 34.3 %, 80-89 years: 39.7 %, and ≥90 years: 42.1 %).
Conclusions: Clinically significant incidental noncardiac findings were newly identified on preprocedural CT in approximately 40 % of patients with severe AS undergoing AVR including 2.5 % of malignancy.
Competing Interests: Declaration of competing interest Kenji Minatoya is a member of the editorial team of Circulation Journal.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE