Long term clinical and radiological outcomes following surgical treatment of symptomatic cranial arachnoid cyst: A population based consecutive cohort study.

Autor: Jaradat A; Neurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan. Electronic address: Aajaradat9@just.edu.jo., Suliman M; Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Ibrahim R; Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Al-Hawamdeh H; Neurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Barbarawi MDA; Neurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Daoud S; Neurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Jarrar S; Neurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan., Jamous M; Neurosurgery Department, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Jazyk: angličtina
Zdroj: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2024 Jul; Vol. 242, pp. 108317. Date of Electronic Publication: 2024 May 06.
DOI: 10.1016/j.clineuro.2024.108317
Abstrakt: Objective: Symptomatic intracranial arachnoid cysts are treated mainly through surgical resection, endoscopic fenestration, or by implanting cystoperitoneal (CP) shunt. However, the use of a specific technique remains controversial. The purpose of this study is to discuss these surgical modalities in symptomatic patients with intracranial arachnoid cysts (ACs) and investigate which has better outcomes and less complications by comparing variable preoperative and postoperative parameters.
Methods: An analysis of thirty-nine symptomatic patients who underwent intracranial arachnoid cyst surgery in the department of neurosurgery between 2009 and 2023 was performed. Patients were retrospectively compared based on age group, gender, anatomical location, laterality, type of intervention, clinical and volumetric changes, postoperative complications and outcome.
Results: Of the 39 patients, 20 patients (51.28 %) received CP shunt. Eleven patients (28.2 %) underwent endoscopic fenestration, and 8 patients (20.5 %) had surgical resection. The age at the time of first operation ranged from 1 month to 59.9 years (mean age: 16.8 years), and the pediatric patients were 25 (64.1 %). The most common initial symptom was headache which was observed in 19 patients (48.7 %), followed by seizure in 12 patients (30.8 %), vomiting in 11 patients (28.2 %), visual dysfunction in 8 patients (20.5 %), drowsiness in 8 patients (20.5 %), visual symptoms in 8 patients (20.5 %), cognitive impairment in 4 patients (10.3 %), focal neurological deficits in 3 patients (7.7 %), and cranial nerve involvement in 1 patient (2.6 %). 24 patients (61.5 %) showed improvement while in 15 patients (38.5 %) the symptoms persisted or worsened. Postoperatively, patients were followed up for an average of one year. The highest improvement rate was noted in endoscopic fenestration with 9 improved patients (81.8 %), followed by surgical resection with 5 symptom-free patients (62.5 %). The worst outcomes were seen in cystoperitoneal shunt with only half of the patients were relieved (50 %). Complications developed in 2 patients (25 %) who underwent surgical resection, 5 patients (45.5 %) who had endoscopic fenestration, and 13 patients (65 %) who had cystoperitoneal shunting.
Conclusion: Endoscopic fenestration has the highest improvement rate, the lowest serious complications along with being the least invasive technique. These features make it the optimal modality in treatment of ACs. Surgical resection or cystoperitoneal shunt can be considered as secondary techniques when patients report unchanged or worsening symptoms.
Competing Interests: Conflict of Interest None.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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