Assessment of triglyceride clearance of haemoperfusion from three cases of hypertriglyceridaemia-induced acute pancreatitis: a case series.

Autor:	Yip WK; Department of Intensive Care and Emergency Medicine, The Third Hospital of Xiamen, Xiamen, Fujian Province, China., Wu B; Department of Intensive Care and Emergency Medicine, The Third Hospital of Xiamen, Xiamen, Fujian Province, China., Ye BH; Department of Intensive Care and Emergency Medicine, The Third Hospital of Xiamen, Xiamen, Fujian Province, China., Chen ML; Department of Intensive Care and Emergency Medicine, The Third Hospital of Xiamen, Xiamen, Fujian Province, China., Wu ZY; Department of Intensive Care and Emergency Medicine, The Third Hospital of Xiamen, Xiamen, Fujian Province, China., Ji CY; Department of Intensive Care and Emergency Medicine, The Third Hospital of Xiamen, Xiamen, Fujian Province, China.
Jazyk:	angličtina
Zdroj:	The Journal of international medical research [J Int Med Res] 2024 May; Vol. 52 (5), pp. 3000605241252607.
DOI:	10.1177/03000605241252607
Abstrakt:	Rapid reduction of plasma triglycerides (TG) is believed to improve the outcome of pancreatitis in the context of hypertriglyceridaemia (HTG)-induced acute pancreatitis (HTG-AP). Previous studies have suggested that haemoperfusion (HP) with the Jafron cartridge series could be effective for reducing TG concentrations in patients with HTG-AP. However, the clearance capacity (CC) for TG removal has not been reported. This case series reports on data from three patients with HTG-AP who underwent HP with HA230 or HA330 cartridges. Blood samples were collected from both before and after the cartridge circuit every 30 min and the CC was calculated. Twelve pairs of blood samples were collected for each type of HP cartridge. The mean ± SD CC of the HA230 cartridge for TG removal in this case series was 0.009781 ± 1.117235 ml/min (95% confidence interval [CI], -0.7000762, 0.7196384 ml). The mean ± SD CC of the HA330 cartridge for TG removal in this case series was 0.344914 ± 1.412183 ml/min (95% CI, -0.5523448, 1.2421721 ml). Based on the findings of this small case series, special caution is advised when considering the use of the HA230 and HA330 cartridges for reducing blood TG concentration pending further conclusive evidence from larger studies. Competing Interests: Declaration of conflicting interestThe authors declare that there are no conflicts of interest.
Databáze:	MEDLINE
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