Cellulose-based CoFe LDH composite as a nano-adsorbent for sulfamethoxazole and cefixime residues: Evaluation of performance, green metrics and cytotoxicity.

Autor: Kotp AA; Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Science (PSAS), Beni-Suef University, Beni-Suef 62511, Egypt., Allam AA; Department of Zoology, Faculty of Science, Beni-suef University, Beni-suef 65211, Egypt. Electronic address: Ahmed.aliahmed@science.bsu.edu.eg., Salah AM; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef 62511, Egypt., Kamal W; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef 62511, Egypt., Essam D; Nanomaterials Science Research Laboratory, Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt., Mahgoub SM; Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Science (PSAS), Beni-Suef University, Beni-Suef 62511, Egypt., Mohamed MA; Hikma Pharmaceutical Company, Beni-Suef, Egypt. Electronic address: MMAbdelfatah@hikma.com., Eldin ZE; Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Science (PSAS), Beni-Suef University, Beni-Suef 62511, Egypt., Alfassam HE; Department of Biology, College of Science, Princess Nourah Bint Abdulrahman University, P.O. BOX 84428, Riyadh 11671, Saudi Arabia. Electronic address: halfassam@pnu.edu.sa., Rudayni HA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh 11623, Saudi Arabia., Alawam AS; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh 11623, Saudi Arabia., Nasr FA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh 11623, Saudi Arabia., Mahmoud R; Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef 62511, Egypt. Electronic address: rehabkhaled@science.bsu.edu.eg.
Jazyk: angličtina
Zdroj: Journal of contaminant hydrology [J Contam Hydrol] 2024 May; Vol. 264, pp. 104364. Date of Electronic Publication: 2024 May 10.
DOI: 10.1016/j.jconhyd.2024.104364
Abstrakt: The increase in antibiotic residues poses a serious threat to ecological and aquatic environments, necessitating the development of cost-effective, convenient, and recyclable adsorbents. In our study, we used cellulose-based layered double hydroxide (LDH) as an efficient adsorbent and nanocarrier for both sulfamethoxazole (SMX) and cefixime (CFX) residues due to their biodegradability and biocompatibility. Chemical processes are measured according to green chemistry metrics to identify which features adhere to the principles. A GREEnness Assessment (ESA), Analytical GREEnness Preparation (AGREEprep), and Analytical Eco-Scale Assessments (ESA) were used to assess the suitability of the proposed analytical method. We extensively analyzed the synthesized CoFe LDH/cellulose before and after the adsorption processes using XRD, FTIR, and SEM. We investigated the factors affecting the adsorption process, such as pH, adsorbent dose, concentrations of SMX and CFX and time. We studied six nonlinear adsorption isotherm models at pH 5 using CoFe LDH, which showed maximum adsorption capacities (qmax) of 272.13 mg/g for SMX and 208.00 mg/g for CFX. Kinetic studies were also conducted. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay was performed on Vero cells in direct contact with LDH nanocomposites to evaluate the cytotoxicity and side effects of cellulose-based CoFe LDH. The cellulose-based CoFe LDH nanocomposite demonstrated excellent cytocompatibility and less cytotoxic effects on the tested cell line. These results validate the potential use of these unique LDH-based cellulose cytocompatible biomaterials for water treatment applications. The cost of the prepared adsorbents was investigated.
Competing Interests: Declaration of competing interest None of the authors have conflicts of interest to disclose.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: