Autor: |
Teixeira FHF; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional Evandro Chagas, Rio de Janeiro, RJ, Brazil., Miguel TS; Ophthalmology Department, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil., Soares DM; Ophthalmology Department, Centro de Estudos e Pesquisas Oculistas Associados, Rio de Janeiro, RJ, Brazil., Rocha J; Ophthalmology Department, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Biancardi AL; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional Evandro Chagas, Rio de Janeiro, RJ, Brazil., Andrade FA; Discipline of Uveitis and Autoimmune Diseases, Centro de Estudos e Pesquisas Oculistas Associados, Rio de Janeiro, RJ, Brazil., Curi ALL; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional Evandro Chagas, Rio de Janeiro, RJ, Brazil. |
Abstrakt: |
Sympathetic ophthalmia is a rare and potentially devastating bilateral diffuse granulomatous panuveitis. It is caused by surgical or non-surgical eye injuries and is an uncommon and serious complication of trauma. It is diagnosed clinically and supported by imaging examinations such as ocular ultrasonography and optical coherence tomography. Its treatment consists of immunosuppressive therapy with steroids and sometimes steroid-sparing drugs, such as cyclosporine, azathioprine, cyclophosphamide, and mycophenolate mofetil. Fast and effective management with systemic immunosuppressive agents allows for disease control and achievement of good visual acuity in the sympathizing eye. By contrast, enucleation should be considered only in situations where the injured eye has no light perception or in the presence of severe trauma. In addition to a bibliographic review of this topic, we report six cases involving different immunosuppressive and surgical treatment modalities. |