Neonatal ventriculomegaly: Pathophysiology and management guided with cranial ultrasonography.

Autor: Bravo MC; Department of Neonatology, La Paz University Hospital and Hospital, La Paz Institute for Health Research, Madrid, Spain., Lubian S; Department of Neonatology, Puerta del Mar University Hospital, Biomedical Research and Innovation Institute of Cádiz, Cádiz, Spain.; Department of Child and Mother Health and Radiology, University of Cádiz, Cádiz, Spain., Horsch S; Department of Neonatology, Helios Klinikum Berlin Buch, Berlin, Germany., Cabañas F; Department of Neonatology, Quironsalud Madrid University Hospital.; Biomedical Research Foundation, La Paz University Hospital, Madrid, Spain., de Vries LS; Department of Neonatology, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Neonatology, Leiden University Medical Center, Leiden, the Netherlands.
Jazyk: angličtina
Zdroj: Developmental medicine and child neurology [Dev Med Child Neurol] 2024 Nov; Vol. 66 (11), pp. 1419-1431. Date of Electronic Publication: 2024 May 15.
DOI: 10.1111/dmcn.15955
Abstrakt: Neonatal ventriculomegaly often, but not always, follows intraventricular haemorrhage in infants born preterm. Serial cranial ultrasonography (CUS) is a very useful tool to evaluate the mechanism behind ventricular dilatation, to differentiate several types of cerebrospinal fluid retention, and to guide treatment. This review examines neonatal ventriculomegaly and its definition, pathophysiology, treatment, and prognosis from the perspective of CUS assessment. It also outlines the consensus statements formulated by the EurUS.Brain group, which are based on rounds of expert opinions on neonatal ventriculomegaly management, detailing the need and timing of ventricular access device placement, in the context of posthaemorrhagic ventricular dilation. The pathophysiology of neonatal ventriculomegaly is more complex than previously considered. CUS is a valuable, non-invasive tool to determine pathophysiology, intervention thresholds, and prognosis in neonates with ventriculomegaly. Given new insights into the existence of glymphatics and water circulation in the cerebrum, further research in that area may bring new treatment options. WHAT THIS PAPER ADDS: Cranial ultrasonography has a significant role in better understanding the complex pathophysiology of neonatal ventriculomegaly. The latest research suggests that treating posthaemorrhagic ventricular dilation in its early stages has several advantages. Proper definition, management, and a follow-up plan are essential because they can impact the infant and their family, health care providers, educational systems, and society.
(© 2024 Mac Keith Press.)
Databáze: MEDLINE
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