Cell Therapies and Gene Therapy for Diabetes: Current Progress.
| Autor: | Ghassemifard L; Department of Physiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran., Hasanlu M; Department of Internal Medicine, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran., Parsamanesh N; Metabolic Diseases Research Center, Zanjan University of Medical Sciences, Zanjan, Iran., Atkin SL; Department, Royal College of Surgeons in Ireland Bahrain, Adliya, Bahrain., Almahmeed W; Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates., Sahebkar A; Center for Global health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Current diabetes reviews [Curr Diabetes Rev] 2024 May 13. Date of Electronic Publication: 2024 May 13. |
| DOI: | 10.2174/0115733998292392240425122326 |
| Abstrakt: | The epidemic of diabetes continues to be an increasing problem, and there is a need for new therapeutic strategies. There are several promising drugs and molecules in synthetic medicinal chemistry that are developing for diabetes. In addition to this approach, extensive studies with gene and cell therapies are being conducted. Gene therapy is an existing approach in treating several diseases, such as cancer, autoimmune diseases, heart disease and diabetes. Several reports have also suggested that stem cells have the differentiation capability to functional pancreatic beta cell development in vitro and in vivo, with the utility to treat diabetes and prevent the progression of diabetes-related complications. In this current review, we have focused on the different types of cell therapies and vector-based gene therapy in treating or preventing diabetes. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|