The futuristic applications of transition metal dichalcogenides for cancer therapy.

Autor: Nandy SK; Department of Pharmacology, School of Pharmacy, Techno India University, Kolkata, India., Das S; Department of Pharmacology, School of Pharmacy, Techno India University, Kolkata, India., Pandey S; Department of Chemistry, College of Natural Science, Yeungnam University, Gyeongsan, Republic of Korea.; School of Bioengineering and Food Technology, Faculty of Applied Sciences and Biotechnology, Shoolini University, Solan, India., Kalita P; University of Science and Technology Meghalaya, Ribhoi, India., Gupta MK; Department of Chemistry, School of Basic Sciences, Central University of Haryana, Mahendergarh, India., Kabra A; University Institute of Pharma Sciences, Chandigarh University, Gharuan, Mohali, India., Wadhwa P; School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar - Delhi, Phagwara, India., Kumar D; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, India.
Jazyk: angličtina
Zdroj: Luminescence : the journal of biological and chemical luminescence [Luminescence] 2024 May; Vol. 39 (5), pp. e4771.
DOI: 10.1002/bio.4771
Abstrakt: The second-most common cause of death resulting from genetic mutations in DNA sequences is cancer. The difficulty in the field of anticancer research is the application of the traditional methods, which also affects normal cells. Mutations, genetic replication alterations, and chromosomal abnormalities have a direct impact on the effectiveness of anticancer drugs at different stages. Presently, therapeutic techniques utilize nanotechnology, transition metal dichalcogenides (TMDCs), and robotics. TMDCs are being increasingly employed in tumor therapy and biosensing applications due to their biocompatibility, adjustable bandgap, versatile functionality, exceptional photoelectric properties, and wide range of applications. This study reports the advancement of nanoplatforms based on TMDCs that are specifically engineered for responsive and intelligent cancer therapy. This article offers a thorough examination of the current challenges, future possibilities for theranostic applications using TMDCs, and recent progress in employing TMDCs for cancer therapy. Currently, there is significant interest in two-dimensional (2D) TMDCs nanomaterials as ultrathin unique physicochemical properties. These materials have attracted attention in various fields, including biomedicine. Due to their inherent ability to absorb near-infrared light and their exceptionally large surface area, significant efforts are being made to prepare multifunctional nanoplatforms based on 2D TMDCs.
(© 2024 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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