The association between referral by specialists in oral diagnosis on survival rates of patients with oral cancer: A retrospective cohort study.

Autor: Sousa-Neto SS; Laboratory of Oral Pathology, School of Dentistry, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Martins AFL; Department of Oral Diagnosis, School of Dentistry, Universidade Evangélica de Goiás, Anápolis, Goiás, Brazil., Moreira VHLO; Laboratory of Oral Pathology, School of Dentistry, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Pereira JGB; Laboratory of Oral Pathology, School of Dentistry, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Freitas NMA; Department of Radiotherapy, Araujo Jorge Cancer Hospital, Goiânia, Goiás, Brazil., Curado MP; Department of Epidemiology, International Research Center, A.C. Camargo Cancer Center, São Paulo, Brazil., Leles CR; Department of Prevention and Oral Rehabilitation, School of Dentistry, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Mendonça EF; Laboratory of Oral Pathology, School of Dentistry, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
Jazyk: angličtina
Zdroj: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology [J Oral Pathol Med] 2024 Jul; Vol. 53 (6), pp. 358-365. Date of Electronic Publication: 2024 May 14.
DOI: 10.1111/jop.13546
Abstrakt: Background: To assess the influence of diagnosis and referral provided by specialists in oral diagnosis on disease-free survival and overall survival of patients with oral cancer.
Methods: A cohort of 282 patients with oral cancer treated at a regional cancer hospital from 1998 to 2016 was analyzed retrospectively. The referral register of the patients was analyzed and assigned to two groups: (1) those referred by oral diagnosis specialists (n = 129), or (2) those referred by nonspecialized professionals (n = 153). The cancer treatment evolution was assessed from the patients' records, and the outcome was registered concerning cancer recurrence and death. Sociodemographic and clinicopathological variables were explored as predictors of disease-free survival and overall survival.
Results: Group 1 exhibited lower T stages and a reduced incidence of regional and distant metastases. Surgery was performed in 75.2% of cases in Group 1, while in Group 2, the rate was 60.8%. Advanced T stages and regional metastases reduced the feasibility of surgery. Higher TNM stages and tumor recurrence were associated with decreased disease-free survival, while surgical intervention was a protective factor. Higher TNM stage had a negative impact on the overall survival.
Conclusion: Specialized oral diagnosis did not directly impact disease-free survival and overall survival and did not influence the indication of surgery in oral cancer; however, it was associated with the diagnosis of early tumors and better prognosis.
(© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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