A rare case of epithelioid angiosarcoma.

Autor: Correia AM; Surgical Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal., Ribas Fernandes R; General Surgery Department, Hospital das Forças Armadas - Pólo do Porto, Portugal., Vidoedo JC; Vascular Surgery Department, Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal., Guimarães J; Surgical Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal., Almeida Pinto J; Vascular Surgery Department, Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.
Jazyk: angličtina
Zdroj: Portuguese journal of cardiac thoracic and vascular surgery [Port J Card Thorac Vasc Surg] 2024 May 13; Vol. 31 (1), pp. 47-51. Date of Electronic Publication: 2024 May 13.
DOI: 10.48729/pjctvs.301
Abstrakt: Epithelioid angiosarcoma is a rare high-grade vascular neoplasm with a poor prognosis. We present an anticoagulated 77-year-old man, with a history of popliteal/soleal vein thrombosis in the previous month, complaining of ipsilateral persistent lower limb pain and claudication. Absent popliteal/distal pulses prompted an arterial doppler ultrasound (DUS), revealing thrombosis of the distal superficial femoral artery and a popliteal mass. As the arterial wall's integrity could not be appropriately evaluated by DUS, adventitial cystic disease of the popliteal artery was suspected. Computed tomography angiography and magnetic resonance imaging findings were also suggestive. Due to refractory pain, he was submitted to a popliteal mass excision along with a femoral-posterior tibial bypass. Pathology revealed an epithelioid angiosarcoma. He was referred to a Sarcoma Center, requiring hospitalization for agitation and fever. A positron emission tomography (PET) scan revealed extensive lower limb disease persistence and distant metastases. He died on the 56th day after surgery. To our knowledge, there are only 15 cases of angiosarcoma of the popliteal artery described in the literature. Ours stands out as the first one unrelated to a popliteal aneurysm. Being a highly-aggressive tumor, an early diagnosis is challenging but essential to a successful treatment, warranting the need for suspicion of this neoplasm. An early core biopsy or surgical sample may expedite the diagnosis.
Databáze: MEDLINE