Operative Time and Accrual of Postoperative Complications in Minimally Invasive Versus Open Myomectomy.

Autor:	Applebaum J; Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania (Drs. Applebaum and Ewy), Philadelphia, Pennsylvania. Electronic address: Jeremy.applebaum@pennmedicine.upenn.edu., Kim EK; Division of Urogynecology, Department of Obstetrics and Gynecology, Brigham and Women's Hospital (Dr. Kim), Boston, Massachusetts., Ewy J; Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania (Drs. Applebaum and Ewy), Philadelphia, Pennsylvania., Humphries LA; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania (Drs. Humphries and Shah), Philadelphia, Pennsylvania., Shah DK; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania (Drs. Humphries and Shah), Philadelphia, Pennsylvania.
Jazyk:	angličtina
Zdroj:	Journal of minimally invasive gynecology [J Minim Invasive Gynecol] 2024 Sep; Vol. 31 (9), pp. 747-755. Date of Electronic Publication: 2024 May 11.
DOI:	10.1016/j.jmig.2024.05.010
Abstrakt:	Study Objective: To compare the prevalence and accrual of 30-day postoperative complications by operative time for open myomectomy (OM) and minimally invasive myomectomy (MIM). Design: Retrospective cohort study SETTING: Hospitals participating in the National Surgical Quality Improvement Program database from January 2015 to December 2021. Patients: Female patients aged ≥18 years undergoing OM or MIM. Interventions: Patients were categorized into OM and MIM cohorts. Covariates associated with operative time and composite complications were identified using general linear model and chi-square or Fisher's exact test as appropriate. Adjusted spline regression was performed as a test of linearity between operative time and composite complications. Adjusted risk ratios of 30-day postoperative individual, minor, major, and composite complications by 60-minute operative time increments were estimated using Poisson regression with robust error variance. Measurements and Main Results: Of 27 728 patients, 11 071 underwent MIM and 16 657 underwent OM. Mean operative times (SD) were 164.6 (82.0) for MIM and 129.2 (67.0) for OM. Raw composite complication rates were 5.5% for MIM and 15.8% for OM. Adjusted spline regression demonstrated linearity between operative time and relative risk of composite postoperative complications for both MIM and OM. MIM had higher adjusted relative risk (aRR, 95% CI) compared to OM of blood transfusion (1.55, 1.45-1.64 versus 1.29, 1.25-1.34), overall minor complications (1.13, 1.03-1.23 versus 1.01, 0.92-1.10), and overall major complications (1.43, 1.35-1.51 versus 1.27, 1.12-1.32). Operative time had greater impact on risk of composite complications for MIM than OM, reaching aRR 2.0 at 296 minutes versus 461 minutes for OM. Conclusion: OM has a higher overall rate of composite, minor, and major complications compared to MIM. While operative time is independently and linearly associated with postoperative complications with myomectomy regardless of approach, optimizing surgical efficiency for MIM may be more critical than for OM. (Copyright © 2024 AAGL. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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