A Case Report of a Uterine Smooth Muscle Tumor of Undetermined Malignant Potential (STUMP): A Diagnostic Dilemma and Management Challenges.

Autor: Hadi B; Obstetrics and Gynecology, College of Medicine, Mustansiriyah University, Baghdad, IRQ., Nori W; Obstetrics and Gynecology, College of Medicine, Mustansiriyah University, Baghdad, IRQ., Ibrahem H; Oral Medicine, College of Dentistry, Ashur University, Baghdad, IRQ., Helmi ZR; Obstetrics and Gynecology, College of Medicine, Mustansiriyah University, Baghdad, IRQ.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Apr 11; Vol. 16 (4), pp. e58067. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
DOI: 10.7759/cureus.58067
Abstrakt: Uterine smooth muscle tumors of undetermined malignant potential (STUMPs) are an uncommon kind of uterine smooth muscle tumor. It is distinguished by histopathologic and morphologic characteristics that are in between those of a benign leiomyoma and a malignant leiomyosarcoma. From a clinical standpoint, the clinical presentation of STUMP is similar to that of a fibroid. The diagnosis is usually confirmed after surgery. Here, we report the case of a 39-year-old woman who experienced increased menorrhagia, back pain, and pressure sensations during the past six months. She had a well-defined, freely movable lump in her lower abdomen, measuring the size of a 22-cm uterus. The patient exhibited pallor, and her imaging scan showed the presence of an intramural posterior uterine solid mass indistinguishable from fibroid measuring 8.5 × 9 cm. Goserelin acetate (Zoladex 3.6 mg implant) was recommended for a duration of six months. The patient experienced a significant amelioration in menorrhagia and discomfort. However, no reduction in the size of the mass was observed. Myomectomy was made for the suspicion of a malignant transformation. The histology examination confirmed the diagnosis of a STUMP; a hysterectomy was undergone, and the procedure went smoothly. The patient was discharged home in good condition with instructions for long-term follow-up due to a risk of recurrence of about 7%. The lack of standardized and clear clinical and diagnostic criteria for STUMP adds challenges to their management.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Hadi et al.)
Databáze: MEDLINE