Dataset of weekly intra-treatment diffusion weighted imaging in head and neck cancer patients treated with MR-Linac.

Autor: El-Habashy DM; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. dina.elhabashy89@gmail.com.; Department of Clinical Oncology and Nuclear Medicine, Menoufia University, Shebin Elkom, Egypt. dina.elhabashy89@gmail.com., Wahid KA; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., He R; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., McDonald B; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mulder SJ; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ding Y; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Salzillo T; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lai SY; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Molecular and Cellular Oncology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Christodouleas J; Elekta AB, Stockholm, Sweden., Dresner A; Philips Healthcare MR Oncology, Cleveland, Ohio, USA., Wang J; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Naser MA; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Fuller CD; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. cdfuller@mdanderson.org., Mohamed ASR; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ASMohamed@mdanderson.org.; Department of Radiation Oncology, Baylor College of Medicine, Houston, TX, USA. ASMohamed@mdanderson.org.
Jazyk: angličtina
Zdroj: Scientific data [Sci Data] 2024 May 11; Vol. 11 (1), pp. 487. Date of Electronic Publication: 2024 May 11.
DOI: 10.1038/s41597-024-03217-z
Abstrakt: Radiation therapy (RT) is a crucial treatment for head and neck squamous cell carcinoma (HNSCC); however, it can have adverse effects on patients' long-term function and quality of life. Biomarkers that can predict tumor response to RT are being explored to personalize treatment and improve outcomes. While tissue and blood biomarkers have limitations, imaging biomarkers derived from magnetic resonance imaging (MRI) offer detailed information. The integration of MRI and a linear accelerator in the MR-Linac system allows for MR-guided radiation therapy (MRgRT), offering precise visualization and treatment delivery. This data descriptor offers a valuable repository for weekly intra-treatment diffusion-weighted imaging (DWI) data obtained from head and neck cancer patients. By analyzing the sequential DWI changes and their correlation with treatment response, as well as oncological and survival outcomes, the study provides valuable insights into the clinical implications of DWI in HNSCC.
(© 2024. The Author(s).)
Databáze: MEDLINE
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