Post-Blink Blur Time-A Simple Test to Detect Dry Eye-Related Visual Disturbances.

Autor: Petriček I; Department of Ophthalmology, Zagreb University Hospital Center, 10000 Zagreb, Croatia.; School of Medicine, University of Zagreb, 10000 Zagreb, Croatia., Lešin Gaćina D; Department of Ophthalmology, Zagreb University Hospital Center, 10000 Zagreb, Croatia., Tomić M; Department of Diabetes and Endocrinology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, 10000 Zagreb, Croatia., Bulum T; School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.; Department of Diabetes and Endocrinology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, 10000 Zagreb, Croatia., Bešlić I; Department of Ophthalmology, Zagreb University Hospital Center, 10000 Zagreb, Croatia., Vidas Pauk S; Department of Ophthalmology, Zagreb University Hospital Center, 10000 Zagreb, Croatia.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2024 Apr 24; Vol. 13 (9). Date of Electronic Publication: 2024 Apr 24.
DOI: 10.3390/jcm13092473
Abstrakt: Background : Dry eye disease (DED) stands out as one of the most common eye conditions encountered in clinical settings. This study aimed to determine the diagnostic ability and feasibility of post-blink blur time (PBBT) in detecting patients with DED symptoms. Methods : The study included 200 subjects, 100 with and 100 without DED symptoms defined by the Schein questionnaire, who underwent assessment of DED signs [visual acuity, PBBT, conjunctival hyperemia, lid-parallel conjunctival folds-LIPCOF, tear film break-up time-TBUT, fluorescein corneal staining, and meibum score]. Results : DED subjects had a lower PBBT than controls ( p < 0.001), with subjective (6 (1-45) s vs. 8 (1-70) s) and objective (6 (2-33) s vs. 8 (2-50) s) PBBT measurements being similar between repeats. The correlations between subjective and objective PBBT measurements were significantly positive (R = 0.873, p < 0.001). Subjective PBBT was negatively related to the Schein questionnaire (R = -0.217, p = 0.002), conjunctival hyperemia (R = -0.105, p = 0.035), and corneal staining (R = -0.153, p = 0.031), while positively related to the TBUT (R = 0.382, p < 0.001) and meibum score (R = 0.106, p = 0.033). Logistic regression analysis showed DED symptoms were significantly associated with subjective PBBT (AOR 0.91, p = 0.001), TBUT (AOR 0.79, p < 0.001), meibum score (AOR 0.65, p = 0.008), LIPCOF (AOR 1.18, p = 0.002) and corneal staining (AOR 1.14, p = 0.028). Conclusions : Subjective self-reported PBBT is a reliable and non-invasive screening test for evaluating time-wise changes in visual acuity and detecting a tear film dysfunction.
Databáze: MEDLINE
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