Evaluation of placenta and fetal lung using shear wave elastography in gestational diabetes mellitus: An innovative approach.

Autor:	Bayraktar B; Department of Obstetrics and Gynecology, Division of Perinatology, Ankara Etlik City Hospital Ankara, Ankara, Turkey.; Department of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Izmir, Turkey., Golbasi H; Department of Obstetrics and Gynecology, Division of Perinatology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Turkey, Izmir, Turkey.; Department of Obstetrics and Gynecology, Division of Perinatology, Izmir Bakircay University Cigli Regional Education Hospital Izmir, Turkey, Izmir, Turkey., Omeroglu I; Department of Obstetrics and Gynecology, Division of Perinatology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Turkey, Izmir, Turkey., Golbasi C; Department of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Izmir, Turkey.; Department of Obstetrics and Gynecology, Izmir Tınaztepe University Faculty of Medicine, Izmir, Turkey, Izmir, Turkey., Tuncer Can S; Department of Obstetrics and Gynecology, Division of Perinatology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Turkey, Izmir, Turkey., Ince O; Department of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Izmir, Turkey.; Deparment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Hacettepe University, Ankara, Turkey.; Department of Statistics, Middle East Technical University, Faculty of Arts and Science, Ankara, Turkey., Bayraktar MG; Department of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Izmir, Turkey.; Department of Obstetrics and Gynecology, University of Health Sciences Gulhane Training and Research Hospital Ankara, Ankara, Turkey., Ozer M; Department of Obstetrics and Gynecology, Division of Perinatology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Turkey, Izmir, Turkey., Ekin A; Department of Obstetrics and Gynecology, Division of Perinatology, University of Health Sciences Tepecik Training and Research Hospital Izmir, Turkey, Izmir, Turkey.
Jazyk:	angličtina
Zdroj:	Ultraschall in der Medizin (Stuttgart, Germany : 1980) [Ultraschall Med] 2024 Nov 04. Date of Electronic Publication: 2024 Nov 04.
DOI:	10.1055/a-2323-0941
Abstrakt:	Purpose: This study aims to investigate placental and fetal lung stiffness in pregnant women with and without gestational diabetes, considering the well-established delay in fetal lung maturation associated with gestational diabetes. Materials and Methods: This prospective cohort study was conducted at a tertiary center and included pregnant women who underwent a 75-gram oral glucose tolerance test between 24-28 weeks of gestation. Elastography measurements were performed using point shear wave elastography (pSWE). Results: The study included 60 pregnant women diagnosed with gestational diabetes and 60 pregnant women in the control group. The SWE velocity of the peripheral placenta, central placenta, and lung was higher in the gestational diabetes group compared to the control group. Furthermore, the SWE velocity of the peripheral placenta, central placenta, and lung was higher in newborns with neonatal respiratory morbidity. Based on the ROC analysis of patients with gestational diabetes, the AUC for lung SWE velocity was 0.88 (cut-off 12.4 kPa, 95% CI: 0.77-0.99, p<0.001) with a sensitivity of 71.4% and specificity of 95.6% for predicting neonatal respiratory morbidity. Conclusion: Fetal placental and lung stiffness increase in fetuses of pregnant women with diabetes. Moreover, higher fetal lung stiffness during the fetal period is associated with increased neonatal respiratory morbidity. Competing Interests: The authors declare that they have no conflict of interest. (Thieme. All rights reserved.)
Databáze:	MEDLINE
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