Italian S3-Guideline on the treatment of Atopic Eczema - Part 1: Systemic therapy, adapted from EuroGuiDerm by the Italian Society of Dermatology and STD (SIDEMAST), the Italian Association of Hospital Dermatologists (ADOI) and the Italian Society of Allergological and Environmental Dermatology (SIDAPA).

Autor: Argenziano G; Dermatology Unit, University of Campania Luigi Vanvitelli, Naples, Italy., Cusano F; Dermatology Unit, G. Rummo Hospital, Benevento, Italy., Corazza M; Section of Dermatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy., Amato S; Department of Dermatology and Sexually Transmitted Diseases, ARNAS-Palermo, Palermo, Italy., Amerio P; Section of Dermatology, Department of Medicine and Aging Science, G. D'Annunzio University, Chieti, Italy., Naldi L; Dermatology Unit, San Bortolo Hospital, Vicenza, Italy., Patruno C; Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy., Pigatto PD; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy., Quaglino P; University of Turin Medical School, Department of Medical Sciences, Dermatologic Clinic, Turin, Italy., Gisondi P; Dermatology and Venereology Section, Department of Medicine, University of Verona, Verona, Italy., Chiricozzi A; Unit of Dermatology, Department of Medical and Surgical Sciences, IRCCS A. Gemelli University Polyclinic Foundation, Rome, Italy.; Unit of Dermatology, Department of Translational Medicine and Surgery, Sacred Heart Catholic University, Rome, Italy., Tonon F; Department of Dermatology, University of Brescia, Brescia, Italy., Stingeni L; Section of Dermatology, Department of Medicine, University of Perugia, Perugia, Italy., Calzavara-Pinton P; Department of Dermatology, University of Brescia, Brescia, Italy - piergiacomo.calzavarapinton@unibs.it., Wollenberg A; Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany.; Department of Dermatology, Free University of Brussel (VUB), Brussels University Hospital (UZ Brussel), Brussels, Belgium., Kinberger M; Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Arents BW; European Federation of Allergy and Airways Diseases Patients' Associations (EFAefa), Brussels, Belgium., Aszodi N; Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany., Avila Valle GL; Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Barbarot S; Department of Dermatology, CHU Nantes, UMR 1280 PhAN, INRAE, Nantes University, Nantes, France., Bieber T; Department of Dermatology and Allergy, University Hospital of Bonn, Bonn, Germany., Brough HA; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, UK.; Paediatric Allergy Group, Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK., Christen-Zäch S; University Hospital Lausanne, Lausanne, Switzerland., Deleuran M; Aarhus University Hospital, Aarhus, Denmark., Dittmann M; Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Dressler C; Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Fink-Wagner AH; Global Allergy and Airways Diseases Patient Platform (GAA PP), Vienna, Austria., Fosse N; Department of Dermatology, University Hospital Basel, Basel, Switzerland., Gáspár K; Department of Dermatology of the University of Debrecen, Debrecen, Hungary., Gerbens LA; Department of Dermatology, Amsterdam UMC (University Medical Centers), Amsterdam, the Netherlands., Gieler U; Department of Dermatology, University of Giessen, Giessen, Germany., Girolomoni G; Dermatology and Venereology Section, Department of Medicine, University of Verona, Verona, Italy., Gregoriou S; Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece., Mortz CG; Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark., Nast A; Division of Evidence-Based Medicine (dEBM), Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Nygaard U; Department of Dermato-Venerology, Aarhus University Hospital, Aarhus, Denmark., Redding M; Eczema Outreach Support, Linlithgow, UK., Rehbinder EM; Dermatology Department, Oslo University Hospital, Oslo, Norway., Ring J; Department of Dermatology Allergology Biederstein, Technical University Munich, Munich, Germany., Rossi M; Dermatology Unit, Spedali Civili Hospital Brescia, Brescia, Italy., Serra-Baldrich E; Dermatology, Hospital of Sant Pau, Barcelona, Spain., Simon D; Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Szalai ZZ; Pediatric Dermatology Unit, Heim Pa'l National Children's Institute Budapest, Budapest, Hungary., Szepietowski JC; Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland., Torrelo A; Hospital Infantil Niño Jesús, Madrid, Spain., Werfel T; Hannover Medical School, Hannover, Germany., Flohr C; St John's Institute of Dermatology, King's College London, London, UK.; Guy's and St Thomas' NHS Foundation Trust, London, UK.
Jazyk: angličtina
Zdroj: Italian journal of dermatology and venereology [Ital J Dermatol Venerol] 2024 Jun; Vol. 159 (3), pp. 223-250. Date of Electronic Publication: 2024 May 10.
DOI: 10.23736/S2784-8671.24.07664-3
Abstrakt: SIDeMaST (Società Italiana di Dermatologia Medica, Chirurgica, Estetica e delle Malattie Sessualmente Trasmesse) contributed to the development of the present guideline on the systemic treatment of chronic plaque psoriasis. With the permission of EuroGuiDerm, SIDeMaST adapted the guideline to the Italian healthcare context to supply a reliable and affordable tool to Italian physicians who take care of patients affected by atopic dermatitis. The evidence- and consensus-based guideline on atopic eczema was developed in accordance with the EuroGuiDerm Guideline and Consensus Statement Development Manual. Four consensus conferences were held between December 2020 and July 2021. Twenty-nine experts (including clinicians and patient representatives) from 12 European countries participated. This first part of the guideline includes general information on its scope and purpose, the health questions covered, target users and a methods section. It also provides guidance on which patients should be treated with systemic therapies, as well as recommendations and detailed information on each systemic drug. The systemic treatment options discussed in the guideline comprise conventional immunosuppressive drugs (azathioprine, ciclosporin, glucocorticosteroids, methotrexate and mycophenolate mofetil), biologics (dupilumab, lebrikizumab, nemolizumab, omalizumab and tralokinumab) and janus kinase inhibitors (abrocitinib, baricitinib and upadacitinib). Part two of the guideline will address avoidance of provocation factors, dietary interventions, immunotherapy, complementary medicine, educational interventions, occupational and psychodermatological aspects, patient perspective and considerations for pediatric, adolescent, pregnant and breastfeeding patients.
Databáze: MEDLINE