Polymeric membrane potentiometric sensors based on template-removal-free imprinted receptors for determination of antibiotics.

Autor:	Wang X; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai, Shandong 264003, P. R. China. rnliang@yic.ac.cn.; University of Chinese Academy of Sciences, Beijing, 100049, P. R. China., Cui G; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai, Shandong 264003, P. R. China. rnliang@yic.ac.cn., Liang R; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai, Shandong 264003, P. R. China. rnliang@yic.ac.cn., Qin W; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai, Shandong 264003, P. R. China. rnliang@yic.ac.cn.
Jazyk:	angličtina
Zdroj:	Analytical methods : advancing methods and applications [Anal Methods] 2024 May 23; Vol. 16 (20), pp. 3240-3248. Date of Electronic Publication: 2024 May 23.
DOI:	10.1039/d4ay00263f
Abstrakt:	Currently, Nernstian-response-based polymeric membrane potentiometric sensors using molecularly imprinted polymers (MIPs) as receptors have been successfully developed for determination of organic ionic species. However, the preparation of these MIP receptors usually involves tedious and time-consuming template-removal procedures. Herein, a template-removal-free MIP is proposed and used as a receptor for fabrication of a potentiometric sensor. The proposed methodology not only significantly shortens the preparation time of MIP-based potentiometric sensors but also improves the batch-to-batch reproducibility of these sensors. By using antibiotic vancomycin as a model, the new concept offers a linear concentration range of 1.0 × 10 -7 to 1.0 × 10 -4 mol L -1 with a detection limit of 2.51 × 10 -8 mol L -1 . It can be expected that the template-removal-free MIP-based sensing strategy could lay the foundation for simple fabrication of electrochemical sensors without the need for template removal such as potentiometric and capacitive sensors and ion-sensitive field-effect transistors.
Databáze:	MEDLINE
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