Prevalence and Associated Factors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy.

Autor:	Abdulkhaleq MM; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Alshugaig RS; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Farhan DA; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Balubaid IT; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Alkhaldi RA; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Shoaib FM; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Shamaa FM; Faculty of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU., Aldaqal SM; General Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Apr 09; Vol. 16 (4), pp. e57921. Date of Electronic Publication: 2024 Apr 09 (Print Publication: 2024).
DOI:	10.7759/cureus.57921
Abstrakt:	Objectives To determine the prevalence of gastroesophageal reflux disease (GERD) after laparoscopic sleeve gastrectomy (LSG) and associated factors. Methods A cross-sectional study was conducted in different regions around the Kingdom of Saudi Arabia between 2022 and 2023. The questionnaire was distributed among patients who underwent LSG at different periods, ranging from six months to more than two years. The questionnaire comprised a risk factor assessment and the GERD-Health-Related Quality of Life (GERD-HRQL) questionnaire. Results A total of 387 participants with a mean age of 35.7±10.95 were included. The study included 225 females (58.1%) and 162 males (41.9%). The mean preoperative body mass index (BMI) was 44.36±8.07 kg/m 2 , which decreased to 28.78±6.31 kg/m 2 postoperatively. Notably, dissatisfaction with general health surged from 17 (24.6%) preoperatively to 165 (42.6%) postoperatively. Despite no significant difference in GERD-HRQL scores in the group who had preoperative symptoms, 282 (72.9%) reported experiencing heartburn, and 289 (74.7%) reported bloating postoperatively. Postoperatively, 203 (52.5%) reported improved quality of life. Moreover, changes in BMI were strongly correlated with heartburn, dysphagia, odynophagia, and bloating. The postoperative prevalence of GERD was 355 (91.7%), with 318 (82.2%) of participants reporting new-onset symptoms. Sex (P=0.013), age (P=0.024), and hypercholesterolemia (P=0.046) were significantly associated with postoperative GERD severity. Conclusions The majority of participants developed GERD symptoms following surgery, with a significant proportion reporting new-onset symptoms. Sex, age, and hypercholesterolemia have emerged as significant factors for postoperative GERD severity. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Abdulkhaleq et al.)
Databáze:	MEDLINE
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