Frontiers of stem cell engineering for nanotechnology-mediated drug delivery systems.
| Autor: | Baydar SY; Faculty of Engineering and Architecture, Department of Biomedical Engineering, Istanbul Gelisim University, Avcilar, Istanbul, Türkiye.; Life Sciences and Biomedical Engineering Application and Research Centre, Istanbul Gelisim University, Avcilar, Istanbul, Türkiye., Ay HF; Department of Bioengineering, Faculty of Chemistry and Metallurgical, Yildiz Technical University, Istanbul, Türkiye., Cakir R; Department of Bioengineering, Faculty of Chemistry and Metallurgical, Yildiz Technical University, Istanbul, Türkiye.; Biotechnology Institute, Health Institutes of Türkiye (TUSEB), Istanbul, Türkiye. |
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| Jazyk: | angličtina |
| Zdroj: | ADMET & DMPK [ADMET DMPK] 2024 Feb 14; Vol. 12 (2), pp. 225-237. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024). |
| DOI: | 10.5599/admet.2160 |
| Abstrakt: | Background and Purpose: Cell biology approaches have gained a successful integration, development and application of nanotechnology with stem cell engineering and have led to the emergence of a new interdisciplinary field known as stem cell nanotechnology (SCN). Recent studies showed the potential and the advancement of developments for SCN applications in drug delivery systems. Cancer, neurodegenerative, muscle and blood diseases, cell and gene therapies, and tissue engineering and regenerative medicine applications are the important targets of SCN. Experimental Approach: In this overview, we searched the literature using the common online websites for research and read the open access, full-text available articles since 2013. Key Results: The studies vary according to the type of disease they targeted and the strategies they proposed, whether diagnostic or therapeutic. In addition to the use of stem cells, the utilisation of their membranes, secretomes, exosomes and extracellular vesicles with an appropriate nanotechnology strategy is also an aspect of the research. Conclusion: This brief overview of stem cell nanotechnology over the last ten years aims to provide insight into the frontiers of stem cell engineering for nanotechnology-mediated drug delivery systems. Competing Interests: Conflict of interest: Authors declare that there is no conflict of interest. (Copyright © 2024 by the authors.) |
| Databáze: | MEDLINE |
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