Antifungal and antibacterial investigation of quinary Zr Al Fe Co Ni layered double hydroxide and its Al Fe Co Ni quaternary and Fe Co Ni tertiary roots.

Autor:	Mahmoud R; Chemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt radwaraft@yahoo.com rehabkhaled@science.bsu.edu.eg doaae4657@gmail.com., Eldin ZE; Department of Materials Science and Nanotechnology, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef 62511 Egypt zienab_ryad@yahoo.com yasser191919@gmail.com., Khalifa A; Biological Science Department, College of Science, King Faisal University P. O. Box 400 Al-Ahsa 31982 Saudi Arabia.; Botany and Microbiology Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt akhalifa@kfu.edu.sa., Ahmed Anwar AA; Chemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt radwaraft@yahoo.com rehabkhaled@science.bsu.edu.eg doaae4657@gmail.com., GadelHak Y; Department of Materials Science and Nanotechnology, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef 62511 Egypt zienab_ryad@yahoo.com yasser191919@gmail.com., Othman SI; Department of Biology, College of Science, Princess Nourah Bint Abdulrahman University P. O. Box 84428 Riyadh 11671 Saudi Arabia sialothman@pnu.edu.sa., Allam AA; Department of Zoology, Faculty of Science, Beni-suef University Beni-suef 65211 Egypt Ahmed.aliahmed@science.bsu.edu.eg., Essam D; Chemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt radwaraft@yahoo.com rehabkhaled@science.bsu.edu.eg doaae4657@gmail.com., Abo El-Ela FI; Department of Pharmacology, Faculty of Veterinary Medicine, Beni-Suef University 62511 Egypt Fatma.aboel3la@vet.bsu.edu.eg fa.pharma@yahoo.com., Aleem Abdel Aziz SA; Department of Hygiene, Zoonoses and Epidemiology, Faculty of Veterinary Medicine, Beni-Suef University Beni-Suef 62511 Egypt abdelaziz.sahar@yahoo.com., Zaher A; Environmental Science and Industrial Development Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef 62511 Egypt amal_2006z@yahoo.com.
Jazyk:	angličtina
Zdroj:	RSC advances [RSC Adv] 2024 May 07; Vol. 14 (21), pp. 14815-14834. Date of Electronic Publication: 2024 May 07 (Print Publication: 2024).
DOI:	10.1039/d4ra00508b
Abstrakt:	Layered double hydroxides (LDH) are promising 2D nanomaterials being investigated for several engineering and biomedical applications. In this work, quinary Zr Al Fe Co Ni LDH and its Al Fe Co Ni LDH quaternary and Fe Co Ni LDH tertiary roots were prepared and characterized. All samples showed an aggregated, layered morphology with zero surface charge and approximately 300 nm of hydrodynamic size. BET surface area of Al Fe Co Ni LDH showed a remarkable value of 143.25 m 2 g -1 as opposed to 26.2 m 2 g -1 and 45.4 m 2 g -1 for Fe Co Ni LDH and Zr Al Fe Co Ni LDH, respectively. The antimicrobial activity of the prepared samples was assessed against the many pathogenic bacteria; Bacillus ( B. ) subtilis , Escherichia ( E. ) coli , Haemophilus ( H. ) influenza , Listeria ( L. ) monocytogenes , Staphylococcus ( S. ) aureus , and Streptococcus ( St. ) pneumonia , and six fungal species. Furthermore, anti-biofilm activity, growth curve assay, and effect of UV illumination were examined against various pathogenic microbes. Zr Al Fe Co Ni displayed remarkable antibacterial activity, as indicated by the lowest values of the minimum inhibitory concentrations (MIC) of 4-166.7 μg mL -1 . Results for fungal strains varied in terms of their susceptibilities for the different samples tested. Zn Al Fe Co Ni was able to inhibit the biofilm formation of S. aureus (96.09%), E. coli (98.32%), and Candida ( C. ) albicans (95.93%). This study shown that certain LDH categories, particularly Zr Al Fe Co Ni, may be promising antibacterial agents against variety of pathogenic microorganisms that cause serious infections. Competing Interests: None of the authors have a conflict of interest to disclose. (This journal is © The Royal Society of Chemistry.)
Databáze:	MEDLINE
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