Facile Synthesis of Silver Nanoparticles From Sustainable Sargassum sp. Seaweed Material and Its Anti-inflammatory Application.

Autor: S K; Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND., A G; Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND., I G K I; Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND., S V; Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND., P S; Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND., S B; Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Apr 07; Vol. 16 (4), pp. e57754. Date of Electronic Publication: 2024 Apr 07 (Print Publication: 2024).
DOI: 10.7759/cureus.57754
Abstrakt: Background Sustainable and environmentally friendly methods of producing nanoparticles are now being investigated by scientists. Because there are so many marine renewable resources, scientists are focusing their attention on studying seagrass, seaweed, mangroves, marine macroalgae, and microalgae. An exciting new frontier in research involves the synthesis of nanoparticles using extracts from seaweed. Seaweed extracts are utilized to synthesize silver nanoparticles (Ag NPs), which serve as both reducing and stabilizing agents. Seaweed extracts possess bioactive substances like proteins, polysaccharides, and polyphenols that enable them to effectively convert silver (Ag + ) ions into Ag NPs. Ag NPs derived from  Sargassum seaweed have played an essential role in improving the anti-inflammatory properties of seaweed extracts. This study aimed to investigate the biosynthesis of Ag NPs from  Sargassum  seaweed and evaluate their anti-inflammatory properties. Materials and methods About 50 g of seaweed samples were mixed with 100 mL of distilled water and stirred for 24 hours. Additionally, 1.2 g of silver nitrate (0.120 M) was dissolved in 60 mL of distilled water to make a silver (Ag) solution. A 60 mL solution of silver nitrate (AgNO 3 ) was mixed with a 40 mL solution of seaweed extract in water, and the mixture was stirred with a stirrer for 24 hours. A UV spectrophotometer was used to regularly monitor the reduction of Ag + ions in the solution. Ag NPs were purified using a sequence of centrifugation steps with a duration of 10 minutes at a speed of 2500 revolutions per minute (rpm). To remove moisture from the water-suspended nanoparticles, they were vacuum-dried for 24 hours.  Results The synthesis of Ag NPs from seaweed extract resulted in a noticeable change in the color of the mixture, which went from pale to brown. The alteration in color signifies the reduction of AgNO 3 to Ag + ions, facilitating the creation of Ag NPs. X-ray diffraction (XRD) measurement verified the remarkable crystallinity of the synthesized Ag NPs. Field emission scanning electron microscopy (FESEM) images indicated a spherical, homogeneous structure. The Ag NPs derived from seaweed exhibited significant anti-inflammatory characteristics. Conclusion Utilizing Sargassum sp. seaweed in the biological synthesis of Ag NPs shows promise to develop nanomaterials that can exhibit anti-inflammatory effects. This technique has benefits, such as being environmentally friendly and cost-efficient. Additional research in this area is essential for effectively exploiting the potential of Ag NPs in anti-inflammatory activity.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, S et al.)
Databáze: MEDLINE
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