New insights into targeted therapy of glioblastoma using smart nanoparticles.

Autor: Ghaznavi H; Pharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran., Afzalipour R; Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. reza.afzalipour@hums.ac.ir.; Department of Radiology, Faculty of Para-Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. reza.afzalipour@hums.ac.ir., Khoei S; Finetech in Medicine Research Center, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Sargazi S; Cellular and Molecular Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran.; Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran., Shirvalilou S; Finetech in Medicine Research Center, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Sheervalilou R; Pharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran. sheervalilour@tbzmed.ac.ir.
Jazyk: angličtina
Zdroj: Cancer cell international [Cancer Cell Int] 2024 May 07; Vol. 24 (1), pp. 160. Date of Electronic Publication: 2024 May 07.
DOI: 10.1186/s12935-024-03331-3
Abstrakt: In recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic and therapeutic approaches in the field of cancer. This innovative fusion of biology, medicine, and nanotechnology aims to create diagnostic and therapeutic agents with enhanced safety and efficacy, particularly in the realm of theranostics for various malignancies. Diverse inorganic, organic, and hybrid organic-inorganic nanoparticles, each possessing unique properties, have been introduced into this domain. This review seeks to highlight the latest strides in targeted glioblastoma therapy by focusing on the application of inorganic smart nanoparticles. Beyond exploring the general role of nanotechnology in medical applications, this review delves into groundbreaking strategies for glioblastoma treatment, showcasing the potential of smart nanoparticles through in vitro studies, in vivo investigations, and ongoing clinical trials.
(© 2024. The Author(s).)
Databáze: MEDLINE
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