Aortic pulse wave analysis and functional capacity of heart transplantation candidates: a pilot study.

Autor: Alcici-Moreira AM; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Vitarelli MO; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Velloso TA; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Carvalho-Ribeiro IA; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Dario DM; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Polese JC; Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Guimarães HP; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Pena JLB; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Tuesta M; Exercise and Rehabilitation Sciences Laboratory, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, Chile., de Rezende BA; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil., Rodrigues-Machado MDG; Post-Graduate Program in Health Sciences of Medical Sciences Faculty of Minas Gerais (FCM-MG), Alameda Ezequiel Dias, 275, Belo Horizonte, MG, 30130-110, Brazil. maria.machado@cienciasmedicasmg.edu.br.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 May 07; Vol. 14 (1), pp. 10504. Date of Electronic Publication: 2024 May 07.
DOI: 10.1038/s41598-024-61152-w
Abstrakt: We compared cardiovascular parameters obtained with the Mobil-O-Graph and functional capacity assessed by the Duke Activity Status Index (DASI) before and after Heart Transplantation (HT) and also compared the cardiovascular parameters and the functional capacity of candidates for HT with a control group. Peripheral and central vascular pressures increased after surgery. Similar results were observed in cardiac output and pulse wave velocity. The significant increase in left ventricular ejection fraction (LVEF) postoperatively was not followed by an increase in the functional capacity. 24 candidates for HT and 24 controls were also compared. Functional capacity was significantly lower in the HT candidates compared to controls. Stroke volume, systolic, diastolic, and pulse pressure measured peripherally and centrally were lower in the HT candidates when compared to controls. Despite the significant increase in peripheral and central blood pressures after surgery, the patients were normotensive. The 143.85% increase in LVEF in the postoperative period was not able to positively affect functional capacity. Furthermore, the lower values of LVEF, systolic volume, central and peripheral arterial pressures in the candidates for HT are consistent with the characteristics signs of advanced heart failure, negatively impacting functional capacity, as observed by the lower DASI score.
(© 2024. The Author(s).)
Databáze: MEDLINE