The World Health Organization Reporting System for Pancreaticobiliary Cytopathology: Overview and Summary.

Autor: Centeno BA; Department of Pathology, Moffitt Cancer Center, Tampa, Florida, USA., Saieg M; Santa Casa Medical School, Sao Paulo, Brazil., Siddiqui MT; Department of Pathology, Weill Cornell Medicine, New York, New York, USA., Perez-Machado M; Department of Cellular Pathology, Royal Free Hampstead NHS Trust, London, England., Layfield LJ; Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, Missouri, USA., Weynand B; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Reid MD; Department of Pathology, Emory University Hospital, Atlanta, Georgia, USA., Stelow EB; Department of Pathology, University of Virginia Hospital, Charlottesville, Virginia, USA., Lozano MD; Department of Pathology, Clinica University of Navarra, Pamplona, Spain., Fukushima N; Department of Diagnostic Pathology, Jichi Medical University Hospital, Shimotsuke, Japan., Cree IA; International Agency for Research on Cancer [IARC], World Health Organization, Lyon, France., Mehrotra R; Indian Cancer Genomic Atlas, Centre for Health, Innovation and Policy Foundation, Noida, Uttar Pradesh, India., Schmitt FC; Faculty of Medicine, Department of Pathology, University of Porto, Porto, Portugal.; CINTESIS@RISE, Porto University, Porto, Portugal., Field AS; Department of Anatomical Pathology, St Vincent's Hospital, Sydney, New South Wales, Australia.; University of New South Wales Sydney and University of Notre Dame, Sydney, New South Wales, Australia., Pitman MB; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jazyk: angličtina
Zdroj: Cancer cytopathology [Cancer Cytopathol] 2024 Jul; Vol. 132 (7), pp. 396-418. Date of Electronic Publication: 2024 May 06.
DOI: 10.1002/cncy.22806
Abstrakt: The recently published WHO Reporting System for Pancreaticobiliary Cytopathology (World Health Organization [WHO] System) is an international approach to the standardized reporting of pancreaticobiliary cytopathology, updating the Papanicolaou Society of Cytopathology System for Reporting Pancreaticobiliary Cytology (PSC System). Significant changes were made to the categorization of benign neoplasms, intraductal neoplasms, mucinous cystic neoplasms, and malignant neoplasms considered low grade. Benign neoplasms, such as serous cystadenoma, categorized as Neoplastic: benign in the PSC system, are categorized as Benign/negative for malignancy in the WHO system. Pancreatic neuroendocrine tumor, solid-pseudopapillary neoplasm, and gastrointestinal stromal tumor, categorized as Neoplastic: other in the PSC system, are categorized as Malignant in the WHO System in accord with their classification in the 5th edition WHO Classification of Digestive System Tumours (2019). The two new categories of Pancreaticobiliary Neoplasm Low-risk/grade and Pancreaticobiliary Neoplasm High-risk/grade are mostly limited to intraductal neoplasms and mucinous cystic neoplasms. Low-risk/grade lesions are mucinous cysts, with or without low-grade epithelial atypia. High-risk/grade lesions contain neoplastic epithelium with high-grade epithelial atypia. Correlation with clinical, imaging, and ancillary studies remains a key tenet. The sections for each entity are written to highlight key cytopathological features and cytopathological differential diagnoses with the pathologist working in low resource setting in mind. Each section also includes the most pertinent ancillary studies useful for the differential diagnosis. Sample reports are provided for each category. Finally, the book provides a separate section with risk of malignancy and management recommendations for each category to facilitate decision-making for clinicians.
(© 2024 American Cancer Society.)
Databáze: MEDLINE
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