180- Versus 360-Degree Selective Laser Trabeculoplasty in Open Angle Glaucoma and Ocular Hypertension: A Systematic Review and Meta-Analysis.

Autor:	Zhu D; Department of Ophthalmology, Northwell Health Eye Institute, Great Neck.; Manhattan Eye, Ear, & Throat Hospital., Shah PP; Department of Ophthalmology, Northwell Health Eye Institute, Great Neck., Wong A; Department of Ophthalmology, New York Eye and Ear Infirmary, New York, NY., Zhang C; Department of Ophthalmology, Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, State University of New York, University at Buffalo, Buffalo., Barmas-Alamdari D; Department of Ophthalmology, Northwell Health Eye Institute, Great Neck.; Manhattan Eye, Ear, & Throat Hospital., Bouaziz M; Department of Ophthalmology, Northwell Health Eye Institute, Great Neck.; Manhattan Eye, Ear, & Throat Hospital., Tirsi A; Department of Ophthalmology, Northwell Health Eye Institute, Great Neck.; Manhattan Eye, Ear, & Throat Hospital., Tello C; Department of Ophthalmology, Northwell Health Eye Institute, Great Neck.; Manhattan Eye, Ear, & Throat Hospital.
Jazyk:	angličtina
Zdroj:	Journal of glaucoma [J Glaucoma] 2024 Aug 01; Vol. 33 (8), pp. 566-575. Date of Electronic Publication: 2024 May 06.
DOI:	10.1097/IJG.0000000000002415
Abstrakt:	Prcis: This systematic review and meta-analysis found that 360-degree selective laser trabeculoplasty (SLT) is significantly more effective than 180-degree SLT at reducing intraocular pressure at 1-month and 1-year follow-ups without increased serious adverse event risk. Purpose: To determine the efficacy of 180- versus 360-degree selective laser trabeculoplasty (SLT) in adults with open angle glaucoma (OAG) and ocular hypertension (OHT). Methods: A systematic review was performed using PubMed, Embase, and Scopus databases, from 1995 to December 30, 2023, for studies comparing 180 and 360-degree SLT in adults with OAG and OHT (PROSPERO ID: CRD42024497832). Meta-analyses were performed to calculate nominal percent and raw reductions in intraocular pressure (IOP) between treatment groups at 1-month, 1-year, and 2-year follow-ups, as well as success rates, defined as a 20% or greater IOP reduction. Results: Nine studies with 1044 eyes were included; 491 received 180-degree SLT, and 553 received 360-degree SLT. At the 1-month follow-up, 360-degree SLT reduced IOP by 3.45% more (WMD=3.45; 95% CI: 2.02-4.88; P <0.00001) and 0.87 mm Hg more (WMD=0.87; 95% CI: 0.35-1.38; P =0.0010). At the 1-year follow-up, 360-degree SLT reduced IOP by 4.33% more (WMD=4.33; 95% CI: 2.35-6.32; P <0.0001) and 1.15 mm Hg more (WMD=1.15; 95% CI: 0.25-2.04; P =0.01). At 2 years of follow-up, 360-degree SLT reduced IOP by 4.86% more (WMD=4.86; 95% CI: -0.32, 10.0; P =0.07) and 1.25 mm Hg more (WMD=1.25; 95% CI: -0.29, 2.79; P =0.11); however, the difference was not statistically significant. Compared with 360-degree SLT, 180-degree SLT had a significantly lower success rate (OR=0.50; 95% CI: 0.35-0.72; P =0.0002). There was no difference in serious complications between interventions. Conclusions: 360-degree SLT is more effective than 180-degree SLT at lowering IOP at 1-month and 1-year follow-ups as well as achieving successful IOP control without increased risk of serious complications. Competing Interests: Disclosure: The authors declare no conflict of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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