Deep Electroreductive Chemistry: Harnessing Carbon- and Silicon-based Reactive Intermediates in Organic Synthesis.

Autor:	Zhang W; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Guan W; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Martinez Alvarado JI; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Novaes LFT; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Lin S; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.
Jazyk:	angličtina
Zdroj:	ACS catalysis [ACS Catal] 2023 Jun 16; Vol. 13 (12), pp. 8038-8048. Date of Electronic Publication: 2023 May 31.
DOI:	10.1021/acscatal.3c01174
Abstrakt:	This Viewpoint outlines our recent contribution in electroreductive synthesis. Specifically, we leveraged deeply reducing potentials provided by electrochemistry to generate radical and anionic intermediates from readily available alkyl halides and chlorosilanes. Harnessing the distinct reactivities of radicals and anions, we have achieved several challenging transformations to construct C-C, C-Si, and Si-Si bonds. We highlight the mechanistic design principle that underpinned the development of each transformation and provide a view forward on future opportunities in growing area of reductive electrosynthesis. Competing Interests: The authors declare no competing financial interest.
Databáze:	MEDLINE
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